Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

37 questions · 37 findings · 4 reviews · Musculoskeletal

No studies found 13 · 35.1%GRADE not reported 0 · 0%Very low 6 · 16.2%Low 10 · 27%Moderate 3 · 8.1%High 5 · 13.5%

Probenecid vs allopurinol

Serum urate normalisation ≤ 5 mg/dL (≤ 0.3 mmol/L) ‐ not measured · people with chronic gout

The review found no eligible studies for this question.

1 finding from 1 review

Benzbromarone vs probenecid

Serum urate normalisation ≤ 5 mg/dL (≤ 0.3 mmol/L) · people with chronic gout

Benzbromarone probably leads to higher serum urate normalisation ≤ 5 mg/dL (≤ 0.3 mmol/L) compared with probenecid (moderate certainty).

1 finding from 1 review

Intervention not reported

Etanercept (25 mg) + DMARD · participants with rheumatoid arthritis

The intervention leads to higher etanercept (25 mg) + DMARD (high certainty).

1 finding from 1 review

Intervention not reported

Etanercept (25 mg) · participants with rheumatoid arthritis

The intervention leads to higher etanercept (25 mg) (high certainty).

1 finding from 1 review

Intervention not reported

Etanercept (25 mg) + DMARD · participants with rheumatoid arthritis
1 finding from 1 review