Findings

What do systematic reviews say?

1,970 questions · 2,433 findings · 231 reviews

Sort:Best matchNewest Highest certainty Download CSV

No studies found 303 · 12.5%GRADE not reported 759 · 31.2%Very low 357 · 14.7%Low 476 · 19.6%Moderate 418 · 17.2%High 120 · 4.9%

Angiotensin receptor blockers (ARBs) vs angiotensin‐converting enzyme inhibitors (ACEis)

Hyperkalaemia · patients receiving PD

Angiotensin receptor blockers (ARBs) showed no clear difference in hyperkalaemia compared with angiotensin‐converting enzyme inhibitors (ACEis) (moderate certainty).

1 finding from 1 review

Angiotensin‐converting enzyme inhibitors and angiotensin receptor blockers for preserving residual kidney function in… 2014 · Cochrane Headline outcomes only
RR 1.23 [0.35, 4.4]
2 studies · 144 participants
Moderate

Angiotensin receptor blockers (ARBs) vs conventional therapy

Urinary protein excretion · patients receiving PD

1 finding from 1 review

Angiotensin‐converting enzyme inhibitors and angiotensin receptor blockers for preserving residual kidney function in… 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 66 participants
Low

Angiotensin receptor blockers (ARBs) vs conventional therapy

Kt/V · patients receiving PD

1 finding from 1 review

Angiotensin‐converting enzyme inhibitors and angiotensin receptor blockers for preserving residual kidney function in… 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 76 participants
Moderate

Angiotensin receptor blockers (ARBs) vs conventional therapy

Creatinine clearance · patients receiving PD

1 finding from 1 review

Angiotensin‐converting enzyme inhibitors and angiotensin receptor blockers for preserving residual kidney function in… 2014 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 110 participants
Low

Angiotensin receptor blockers (ARBs) vs conventional therapy

Systolic blood pressure · patients receiving PD

1 finding from 1 review

Angiotensin‐converting enzyme inhibitors and angiotensin receptor blockers for preserving residual kidney function in… 2014 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 110 participants
Moderate

TDF vs AZT

Serious adverse events · patients with initial ART

TDF showed no clear difference in serious adverse events compared with AZT (high certainty).

1 finding from 1 review

Tenofovir or zidovudine in three‐drug combination therapy with one nucleoside reverse transcriptase inhibitor and one… 2010 · Cochrane Headline outcomes only
RR 0.92 [0.6, 1.43]
2 studies · 586 participants
High

TDF vs AZT

Virologic response · patients with initial ART

TDF showed no clear difference in virologic response compared with AZT (high certainty).

1 finding from 1 review

Tenofovir or zidovudine in three‐drug combination therapy with one nucleoside reverse transcriptase inhibitor and one… 2010 · Cochrane Headline outcomes only
RR 2.04 [0.17, 24.84]
2 studies · 586 participants
High

TDF vs AZT

Adherence/tolerability/retention · patients with initial ART

TDF probably leads to higher adherence/tolerability/retention compared with AZT (moderate certainty).

1 finding from 1 review

Tenofovir or zidovudine in three‐drug combination therapy with one nucleoside reverse transcriptase inhibitor and one… 2010 · Cochrane Headline outcomes only
RR 1.17 [1.06, 1.29]
2 studies · 586 participants
Moderate

TDF vs AZT

Immunological response · patients with initial ART

1 finding from 1 review

Tenofovir or zidovudine in three‐drug combination therapy with one nucleoside reverse transcriptase inhibitor and one… 2010 · Cochrane Headline outcomes only
no estimate extracted
1 study · 515 participants
Moderate

TDF vs AZT

Drug resistance · patients with initial ART

It is very uncertain whether TDF changes drug resistance compared with AZT (very low certainty).

1 finding from 1 review

Tenofovir or zidovudine in three‐drug combination therapy with one nucleoside reverse transcriptase inhibitor and one… 2010 · Cochrane Headline outcomes only
RR 20.43 [1.24, 335.9]
1 study · 71 participants
Very low