Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,016 questions · 2,067 findings · 222 reviews · Headline outcomes only

No studies found 471 · 22.8%GRADE not reported 108 · 5.2%Very low 570 · 27.6%Low 458 · 22.2%Moderate 363 · 17.6%High 97 · 4.7%

Intervention not reported

Treatment failure at 1 month or less · patients with acute otitis media

The intervention led to higher treatment failure at 1 month or less; GRADE not reported.

1 finding from 1 review

Intervention not reported

Treatment failure at 8 to 19 days · patients with acute otitis media

The intervention led to higher treatment failure at 8 to 19 days; GRADE not reported.

1 finding from 1 review

Intervention not reported

Treatment failure at 20 to 30 days · patients with acute otitis media

The intervention showed no clear difference in treatment failure at 20 to 30 days; GRADE not reported.

1 finding from 1 review

Intervention not reported

Treatment failure at 8 to 19 days · patients with acute otitis media

The intervention led to higher treatment failure at 8 to 19 days; GRADE not reported.

1 finding from 1 review

Intervention not reported

Treatment failure at 20 to 30 days · patients with acute otitis media

The intervention showed no clear difference in treatment failure at 20 to 30 days; GRADE not reported.

1 finding from 1 review

Intervention not reported

Treatment failure at 3 months or less · patients with acute otitis media

The intervention showed no clear difference in treatment failure at 3 months or less; GRADE not reported.

1 finding from 1 review

Intervention not reported

Treatment failure at 90 days · patients with acute otitis media

The intervention showed no clear difference in treatment failure at 90 days; GRADE not reported.

1 finding from 1 review

Intervention not reported

Treatment failure at 30 to 45 days · patients with acute otitis media

The intervention showed no clear difference in treatment failure at 30 to 45 days; GRADE not reported.

1 finding from 1 review

Intervention not reported

Treatment failure at 1 month or less · patients with acute otitis media

The intervention showed no clear difference in treatment failure at 1 month or less; GRADE not reported.

1 finding from 1 review

Intervention not reported

Treatment failure at 3 months or less · patients with acute otitis media

The intervention showed no clear difference in treatment failure at 3 months or less; GRADE not reported.

1 finding from 1 review

Intervention not reported

Treatment failure at 1 month or less · patients with acute otitis media

The intervention showed no clear difference in treatment failure at 1 month or less; GRADE not reported.

1 finding from 1 review

Fluoroquinolones vs beta‐lactams

Other adverse events clinical criteria · patients with Shigella dysentery

It is very uncertain whether fluoroquinolones changes other adverse events clinical criteria compared with beta‐lactams (very low certainty).

1 finding from 1 review