Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,922 questions · 3,118 findings · 513 reviews

No studies found 574 · 18.4%GRADE not reported 372 · 11.9%Very low 723 · 23.2%Low 854 · 27.4%Moderate 489 · 15.7%High 106 · 3.4%

Acupuncture vs sham

Change in SBP shortly after last session · people with primary hypertension
1 finding from 1 review

Acupuncture vs sham

Change in DBP shortly after last session · people with primary hypertension
1 finding from 1 review

Intervention not reported

Adverse events · people with primary hypertension
1 finding from 1 review

Bispectral index vs treatment guided by clinical assessment alone?

Duration of mechanical ventilation · Mechanically ventilated adults in the intensive care unit

BIS monitoring showed no clear difference in duration of mechanical ventilation (measured in days) compared with clinical assessment (low certainty).

1 finding from 1 review

Ferric sulphate (FS) + mineral trioxide aggregate (MTA) vs Zinc oxide and eugenol (ZOE) pulpectomy

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Ferric sulphate/MTA pulpotomy showed no clear difference in radiological failure compared with zinc oxide and eugenol (ZOE) pulpectomy; GRADE not reported.

1 finding from 1 review

ProRoot MTA vs OrthoMTA

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

ProRoot MTA showed no clear difference in clinical failure compared with orthoMTA; GRADE not reported.

1 finding from 1 review

Mineral trioxide aggregate (MTA) vs Buffered glutaraldehyde

Outcome not reported · Children with extensive decay involving the dental pulp in primary teeth
1 finding from 1 review
  • Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
    6 months
    Assessed pain, soft tissue, mobility, radiolucency, root resorption, pulp canal obliteration (Goyal 2016); no clinical/radiological failure outcome; pain, mobility, radiolucency, root resorption significantly favour MTA
    1 study · 60 participants
    GRADE not reported

Mineral trioxide aggregate (MTA) vs Diode laser

Outcome not reported · Children with extensive decay involving the dental pulp in primary teeth
1 finding from 1 review
  • Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
    6 months
    Assessed pain, soft tissue, mobility, radiolucency, root resorption, premature tooth loss (Niranjani 2015); no clinical/radiological failure outcome; no significant differences (RR 0.33, 0.01 to 7.72)
    1 study · 40 participants
    GRADE not reported

3Mix (ciprofloxacin + metronidazole + minocycline) pulpotomy vs 3Mix pulpectomy

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

3Mix (ciprofloxacin + metronidazole + minocycline) pulpotomy showed no clear difference in clinical failure compared with 3Mix pulpectomy; GRADE not reported.

1 finding from 1 review

Calcium-enriched mixture (CEM) cement vs Mineral trioxide aggregate (MTA)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth
2 findings from 1 review