Findings

What do systematic reviews say?

2,973 questions · 3,072 findings · 410 reviews · Headline outcomes only

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No studies found 559 · 18.2%GRADE not reported 143 · 4.7%Very low 654 · 21.3%Low 833 · 27.1%Moderate 683 · 22.2%High 200 · 6.5%

Staple food fortified with vitamin A plus other micronutrients vs same unfortified staple foods

Any adverse effects (e.g. hypervitaminosis A, as defined by the trialists) · general population over 2 years of age

The review found no eligible studies for this question.

1 finding from 1 review

Fortification of staple foods with vitamin A for vitamin A deficiency 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Staple food fortified with vitamin A plus other micronutrients vs no intervention

Serum/plasma retinol (μmol/L) · general population over 2 years of age

1 finding from 1 review

Fortification of staple foods with vitamin A for vitamin A deficiency 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 318 participants
Low

Staple food fortified with vitamin A plus other micronutrients vs no intervention

Subclinical vitamin A deficiency (serum/plasma retinol 0.70 μmol/L or less) · general population over 2 years of age

It is very uncertain whether staple food fortified with vitamin A plus other micronutrients changes subclinical vitamin A deficiency (serum/plasma retinol 0.70 μmol/L… compared with no intervention (very low certainty).

1 finding from 1 review

Fortification of staple foods with vitamin A for vitamin A deficiency 2019 · Cochrane Headline outcomes only
RR 0.71 [0.52, 0.98]
2 studies · 318 participants
Very low

Staple food fortified with vitamin A plus other micronutrients vs no intervention

Clinical vitamin A deficiency (as defined by night blindness) · general population over 2 years of age

The review found no eligible studies for this question.

1 finding from 1 review

Fortification of staple foods with vitamin A for vitamin A deficiency 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Staple food fortified with vitamin A plus other micronutrients vs no intervention

All‐cause mortality · general population over 2 years of age

The review found no eligible studies for this question.

1 finding from 1 review

Fortification of staple foods with vitamin A for vitamin A deficiency 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Staple food fortified with vitamin A plus other micronutrients vs no intervention

All‐cause morbidity · general population over 2 years of age

The review found no eligible studies for this question.

1 finding from 1 review

Fortification of staple foods with vitamin A for vitamin A deficiency 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Staple food fortified with vitamin A plus other micronutrients vs no intervention

Any adverse effects (e.g. hypervitaminosis A, as defined by the trialists) · general population over 2 years of age

The review found no eligible studies for this question.

1 finding from 1 review

Fortification of staple foods with vitamin A for vitamin A deficiency 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Staple foods fortified with vitamin A vs same unfortified staple foods

Subclinical vitamin A deficiency (serum/plasma retinol 70 μmol/L or less) · general population over 2 years of age

It is very uncertain whether staple foods fortified with vitamin A changes subclinical vitamin A deficiency (serum/plasma retinol 70 μmol/L or… compared with same unfortified staple foods (very low certainty).

1 finding from 1 review

Fortification of staple foods with vitamin A for vitamin A deficiency 2019 · Cochrane Headline outcomes only
RR 0.45 [0.19, 1.05]
2 studies · 993 participants
Very low

Staple foods fortified with vitamin A vs same unfortified staple foods

Clinical vitamin A deficiency (as defined by night blindness) · general population over 2 years of age

It is very uncertain whether staple foods fortified with vitamin A changes clinical vitamin A deficiency (defined as night blindness) compared with same unfortified staple foods (very low certainty).

1 finding from 1 review

Fortification of staple foods with vitamin A for vitamin A deficiency 2019 · Cochrane Headline outcomes only
RR 0.11 [0.01, 1.98]
1 study · 581 participants
Very low

Staple foods fortified with vitamin A vs same unfortified staple foods

All‐cause mortality · general population over 2 years of age

The review found no eligible studies for this question.

1 finding from 1 review

Fortification of staple foods with vitamin A for vitamin A deficiency 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Staple foods fortified with vitamin A vs same unfortified staple foods

All‐cause morbidity · general population over 2 years of age

The review found no eligible studies for this question.

1 finding from 1 review

Fortification of staple foods with vitamin A for vitamin A deficiency 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Staple foods fortified with vitamin A vs same unfortified staple foods

Any adverse effects (e.g. hypervitaminosis A, as defined by the trialists) · general population over 2 years of age

The review found no eligible studies for this question.

1 finding from 1 review

Fortification of staple foods with vitamin A for vitamin A deficiency 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Staple food fortified with vitamin A plus other micronutrients vs same unfortified staple foods

Serum/plasma retinol (μmol/L) · general population over 2 years of age

1 finding from 1 review

Fortification of staple foods with vitamin A for vitamin A deficiency 2019 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 1009 participants
Low

Staple food fortified with vitamin A plus other micronutrients vs same unfortified staple foods

Subclinical vitamin A deficiency (serum/plasma retinol 0.70 μmol/L or less) · general population over 2 years of age

Staple foods fortified with vitamin A plus other micronutrients probably leads to lower subclinical vitamin A deficiency (serum/plasma retinol 0.70 μmol/L… compared with same unfortified staple foods (moderate certainty).

1 finding from 1 review

Fortification of staple foods with vitamin A for vitamin A deficiency 2019 · Cochrane Headline outcomes only
RR 0.27 [0.16, 0.49]
3 studies · 923 participants
Moderate

Staple food fortified with vitamin A plus other micronutrients vs same unfortified staple foods

Clinical vitamin A deficiency (as defined by night blindness) · general population over 2 years of age

The review found no eligible studies for this question.

1 finding from 1 review

Fortification of staple foods with vitamin A for vitamin A deficiency 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Death (all‐cause) · all populations, including pregnant women, from any country

The review found no eligible studies for this question.

1 finding from 1 review

Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Mental development · all populations, including pregnant women, from any country

The review found no eligible studies for this question.

1 finding from 1 review

Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Cognitive function and motor skill development · all populations, including pregnant women, from any country

The review found no eligible studies for this question.

1 finding from 1 review

Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Cretinism · all populations, including pregnant women, from any country

The review found no eligible studies for this question.

1 finding from 1 review

Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Hypothyroidism · all populations, including pregnant women, from any country

The review found no eligible studies for this question.

1 finding from 1 review

Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found