Secondary patency (24 months) · people with peripheral vascular disease requiring above‐knee femoro‐popliteal bypass surgery
Externally supported graft may leads to higher secondary patency (24 months) compared with unsupported graft (low certainty).
1 finding from 1 review
OR 2.25 [1.24, 4.07]
Studies not reported
Low
Limb salvage · people with peripheral vascular disease requiring above‐knee femoro‐popliteal bypass surgery
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Primary patency ( · people with peripheral vascular disease requiring below‐knee femoro‐popliteal bypass surgery
It is very uncertain whether PTFE changes primary patency (24 months) compared with PTFE with vein cuff (very low certainty).
2 findings from 1 review
OR 1.08 [0.58, 2.01]
Studies not reported
Very low
no estimate extracted
Studies not reported
No studies found
Secondary patency (24 months) · people with peripheral vascular disease requiring below‐knee femoro‐popliteal bypass surgery
It is very uncertain whether PTFE changes secondary patency (24 months) compared with PTFE with vein cuff (very low certainty).
1 finding from 1 review
OR 1.22 [0.67, 2.23]
Studies not reported
Very low
Limb salvage · people with peripheral vascular disease requiring below‐knee femoro‐popliteal bypass surgery
PTFE showed no clear difference in limb salvage (24 months) compared with PTFE with vein cuff (low certainty).
1 finding from 1 review
OR 1.34 [0.72, 2.49]
Studies not reported
Low
Secondary patency (24 months) · people with peripheral vascular disease requiring above‐knee femoro‐popliteal bypass surgery
Autologous vein may leads to lower secondary patency (60 months) compared with other graft types (low certainty).
1 finding from 1 review
OR 0.41 [0.22, 0.74]
Studies not reported
Low
Limb salvage · people with peripheral vascular disease requiring above‐knee femoro‐popliteal bypass surgery
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Primary patency ( · people with peripheral vascular disease requiring above‐knee femoro‐popliteal bypass surgery
PTFE showed no clear difference in primary patency (24 months) compared with dacron (low certainty).
2 findings from 1 review
OR 1.23 [0.92, 1.65]
Studies not reported
Low
OR 1.67 [0.96, 2.9]
Studies not reported
Low
Secondary patency (24 months) · people with peripheral vascular disease requiring above‐knee femoro‐popliteal bypass surgery
PTFE may leads to higher secondary patency (24 months) compared with dacron (low certainty).
1 finding from 1 review
OR 1.54 [1.04, 2.28]
Studies not reported
Low
Limb salvage · people with peripheral vascular disease requiring above‐knee femoro‐popliteal bypass surgery
PTFE showed no clear difference in limb salvage (24 months) compared with dacron (low certainty).
1 finding from 1 review
OR 0.82 [0.27, 2.48]
Studies not reported
Low
Overall mortality ( · People with localised rectal carcinoma
Preoperative radiotherapy probably leads to lower overall mortality ( compared with surgery alone (moderate certainty).
1 finding from 1 review
Overall mortality ‐ only total mesorectal excision ( · People with localised rectal carcinoma
Preoperative radiotherapy showed no clear difference in overall mortality ‐ only total mesorectal excision ( compared with surgery alone (low certainty).
1 finding from 1 review
Cause‐specific mortality · People with localised rectal carcinoma
Preoperative radiotherapy showed no clear difference in cause‐specific mortality ( compared with surgery alone (low certainty).
1 finding from 1 review
Local recurrence · People with localised rectal carcinoma
Preoperative radiotherapy probably leads to lower local recurrence ( compared with surgery alone (moderate certainty).
1 finding from 1 review
Curative resection ( · People with localised rectal carcinoma
Preoperative radiotherapy showed no clear difference in curative resection ( compared with surgery alone (low certainty).
1 finding from 1 review
Sphincter preservation ( · People with localised rectal carcinoma
Preoperative radiotherapy showed no clear difference in sphincter preservation ( compared with surgery alone (low certainty).
1 finding from 1 review
Quality of life ( · People with localised rectal carcinoma
1 finding from 1 review
Bradycardia (requiring pharmacological or pacemaker treatment during the period of study drug administration) · adults undergoing cardiac surgery
Alpha‐2 adrenergic agonists probably leads to higher bradycardia (requiring pharmacological or pacemaker treatment during… compared with control (moderate certainty).
1 finding from 1 review
Hypotension (requiring treatment with inotropes or vasopressors during the period of study drug administration) · adults undergoing cardiac surgery
Alpha‐2 adrenergic agonists showed no clear difference in hypotension (requiring treatment with inotropes or vasopressors… compared with control (low certainty).
1 finding from 1 review
Bradycardia (requiring pharmacological or pacemaker treatment during the period of study drug administration) · adults undergoing non‐cardiac surgery
1 finding from 1 review