Findings

What do systematic reviews say?

3,747 questions · 3,943 findings · 594 reviews

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No studies found 784 · 19.9%GRADE not reported 530 · 13.4%Very low 1,040 · 26.4%Low 981 · 24.9%Moderate 444 · 11.3%High 164 · 4.2%

Laparoscopic pyloromyotomy vs open pyloromyotomy

Time to full feeds · infants (< 1 year of age) with hypertrophic pyloric stenosis

1 finding from 1 review

Open versus laparoscopic pyloromyotomy for pyloric stenosis 2021 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 622 participants
Very low

Laparoscopic pyloromyotomy vs open pyloromyotomy

Operating time · infants (< 1 year of age) with hypertrophic pyloric stenosis

1 finding from 1 review

Open versus laparoscopic pyloromyotomy for pyloric stenosis 2021 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 622 participants
Very low

Roux‐en‐Y vs Billroth‐I after distal gastrectomy

Health‐related quality of life · people undergoing distal gastrectomy for gastric cancer

1 finding from 1 review

Roux‐en‐Y versus Billroth‐I reconstruction after distal gastrectomy for gastric cancer 2021 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 695 participants
Low

Roux‐en‐Y vs Billroth‐I after distal gastrectomy

Anastomotic leakage · people undergoing distal gastrectomy for gastric cancer

It is very uncertain whether roux‐en‐Y changes incidence of anastomotic leakage compared with billroth‐I after distal gastrectomy (very low certainty).

1 finding from 1 review

Roux‐en‐Y versus Billroth‐I reconstruction after distal gastrectomy for gastric cancer 2021 · Cochrane Headline outcomes only
RR 0.63 [0.16, 2.53]
5 studies · 711 participants
Very low

Roux‐en‐Y vs Billroth‐I after distal gastrectomy

Weight loss (change in kg weight) · people undergoing distal gastrectomy for gastric cancer

1 finding from 1 review

Roux‐en‐Y versus Billroth‐I reconstruction after distal gastrectomy for gastric cancer 2021 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 541 participants
Low

Roux‐en‐Y vs Billroth‐I after distal gastrectomy

Incidence of bile reflux · people undergoing distal gastrectomy for gastric cancer

Roux‐en‐Y probably leads to lower incidence of bile reflux compared with billroth‐I after distal gastrectomy (moderate certainty).

1 finding from 1 review

Roux‐en‐Y versus Billroth‐I reconstruction after distal gastrectomy for gastric cancer 2021 · Cochrane Headline outcomes only
RR 0.4 [0.25, 0.63]
4 studies · 399 participants
Moderate

Roux‐en‐Y vs Billroth‐I after distal gastrectomy

Length of hospital stay · people undergoing distal gastrectomy for gastric cancer

1 finding from 1 review

Roux‐en‐Y versus Billroth‐I reconstruction after distal gastrectomy for gastric cancer 2021 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 894 participants
Very low

Roux‐en‐Y vs Billroth‐I after distal gastrectomy

Overall postoperative morbidity · people undergoing distal gastrectomy for gastric cancer

Roux‐en‐Y may leads to higher postoperative morbidity compared with billroth‐I after distal gastrectomy (low certainty).

1 finding from 1 review

Roux‐en‐Y versus Billroth‐I reconstruction after distal gastrectomy for gastric cancer 2021 · Cochrane Headline outcomes only
RR 1.47 [1.02, 2.11]
7 studies · 891 participants
Low

Intervention not reported

Interventions · people with liver cirrhosis and oesophageal varices with no history of bleeding

The review found no eligible studies for this question.

1 finding from 1 review

Primary prevention of variceal bleeding in people with oesophageal varices due to liver cirrhosis: a network… 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Portocaval shunt(No direct RCT) · people with liver cirrhosis and oesophageal varices with no history of bleeding

It is very uncertain whether the intervention changes portocaval shunt(No direct RCT) (very low certainty).

1 finding from 1 review

Primary prevention of variceal bleeding in people with oesophageal varices due to liver cirrhosis: a network… 2021 · Cochrane Headline outcomes only
HR 0.51 [0.06, 2.92]
Studies not reported
Very low

Intervention not reported

Sclerotherapy(1 RCT, 85 participants) · people with liver cirrhosis and oesophageal varices with no history of bleeding

It is very uncertain whether the intervention changes sclerotherapy(1 RCT, 85 participants) (very low certainty).

1 finding from 1 review

Primary prevention of variceal bleeding in people with oesophageal varices due to liver cirrhosis: a network… 2021 · Cochrane Headline outcomes only
OR 0.55 [0, 272.05]
Studies not reported
Very low

Intervention not reported

No active intervention(2 RCTs, 256 participants) · people with liver cirrhosis and oesophageal varices with no history of bleeding

It is very uncertain whether the intervention changes no active intervention(2 RCTs, 256 participants) (very low certainty).

1 finding from 1 review

Primary prevention of variceal bleeding in people with oesophageal varices due to liver cirrhosis: a network… 2021 · Cochrane Headline outcomes only
OR 0.28 [0.02, 2.91]
Studies not reported
Very low

Intervention not reported

Sclerotherapy(No direct RCT) · people with liver cirrhosis and oesophageal varices with no history of bleeding

It is very uncertain whether the intervention changes sclerotherapy(No direct RCT) (very low certainty).

1 finding from 1 review

Primary prevention of variceal bleeding in people with oesophageal varices due to liver cirrhosis: a network… 2021 · Cochrane Headline outcomes only
OR 1.19 [0.02, 80.24]
Studies not reported
Very low

Intervention not reported

Beta‐blockers + nitrates(1 RCT, 57 participants) · people with liver cirrhosis and oesophageal varices with no history of bleeding

The intervention may leads to higher beta‐blockers + nitrates(1 RCT, 57 participants) (low certainty).

1 finding from 1 review

Primary prevention of variceal bleeding in people with oesophageal varices due to liver cirrhosis: a network… 2021 · Cochrane Headline outcomes only
OR 3.41 [1.11, 11.28]
Studies not reported
Low

Intervention not reported

No active intervention(No direct RCT) · people with liver cirrhosis and oesophageal varices with no history of bleeding

1 finding from 1 review

Primary prevention of variceal bleeding in people with oesophageal varices due to liver cirrhosis: a network… 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Intervention not reported

Beta‐blockers · people with liver cirrhosis and oesophageal varices with no history of bleeding

The review found no eligible studies for this question.

1 finding from 1 review

Primary prevention of variceal bleeding in people with oesophageal varices due to liver cirrhosis: a network… 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Sclerotherapy(2 RCTs, 90 participants) · people with liver cirrhosis and oesophageal varices with no history of bleeding

1 finding from 1 review

Primary prevention of variceal bleeding in people with oesophageal varices due to liver cirrhosis: a network… 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Intervention not reported

No active intervention(1 RCT, 161 participants) · people with liver cirrhosis and oesophageal varices with no history of bleeding

It is very uncertain whether the intervention changes no active intervention(1 RCT, 161 participants) (very low certainty).

1 finding from 1 review

Primary prevention of variceal bleeding in people with oesophageal varices due to liver cirrhosis: a network… 2021 · Cochrane Headline outcomes only
HR 1.36 [0.35, 5.8]
Studies not reported
Very low

Intervention not reported

No active intervention(1 RCT, 140 participants) · people with liver cirrhosis and oesophageal varices with no history of bleeding

It is very uncertain whether the intervention changes no active intervention(1 RCT, 140 participants) (very low certainty).

1 finding from 1 review

Primary prevention of variceal bleeding in people with oesophageal varices due to liver cirrhosis: a network… 2021 · Cochrane Headline outcomes only
HR 1.14 [0.56, 2.4]
Studies not reported
Very low

Intervention not reported

Sclerotherapy(1 RCT, 141 participants) · people with liver cirrhosis and oesophageal varices with no history of bleeding

It is very uncertain whether the intervention changes sclerotherapy(1 RCT, 141 participants) (very low certainty).

1 finding from 1 review

Primary prevention of variceal bleeding in people with oesophageal varices due to liver cirrhosis: a network… 2021 · Cochrane Headline outcomes only
HR 0.91 [0.44, 1.95]
Studies not reported
Very low