Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,678 questions · 4,859 findings · 283 reviews

No studies found 1,225 · 25.2%GRADE not reported 215 · 4.4%Very low 1,241 · 25.5%Low 1,210 · 24.9%Moderate 776 · 16%High 192 · 4%

Immunoglobulin vs placebo

Mortality (any cause during hospitalisation or · children with respiratory syncytial virus infection

It is very uncertain whether summary of findings table ‐ Immunoglobulins changes mortality (any cause during hospitalisation or compared with placebo (very low certainty).

1 finding from 1 review

Immunoglobulin vs placebo

Adverse events of any severity or seriousness · children with respiratory syncytial virus infection

Summary of findings table ‐ Immunoglobulins showed no clear difference in adverse events of any severity or seriousness compared with placebo (low certainty).

1 finding from 1 review

Summary of findings table ‐ Maintenance ASM vs no maintenance ASM after achieving seizure control

Proportion of infants with repeat seizure before hospital discharge · neonates with clinically diagnosed seizures

It is very uncertain whether summary of findings table ‐ Maintenance ASM changes proportion of infants with repeat seizure before hospital discharge compared with no maintenance ASM after achieving seizure control (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Maintenance ASM vs no maintenance ASM after achieving seizure control

Mortality before hospital discharge · neonates with clinically diagnosed seizures

Summary of findings table ‐ Maintenance ASM showed no clear difference in mortality before hospital discharge compared with no maintenance ASM after achieving seizure control (low certainty).

1 finding from 1 review

Summary of findings table ‐ Maintenance ASM vs no maintenance ASM after achieving seizure control

Mortality at 18‐24 months · neonates with clinically diagnosed seizures

Summary of findings table ‐ Maintenance ASM showed no clear difference in mortality at 18‐24 months compared with no maintenance ASM after achieving seizure control (low certainty).

1 finding from 1 review

Summary of findings table ‐ Maintenance ASM vs no maintenance ASM after achieving seizure control

Neurodevelopmental disability at 18 to 24 months among survivors · neonates with clinically diagnosed seizures

Summary of findings table ‐ Maintenance ASM showed no clear difference in neurodevelopmental disability at 18‐24 months compared with no maintenance ASM after achieving seizure control (low certainty).

1 finding from 1 review

Summary of findings table ‐ Maintenance ASM vs no maintenance ASM after achieving seizure control

Proportion of infants who develop epilepsy post‐discharge · neonates with clinically diagnosed seizures

Summary of findings table ‐ Maintenance ASM showed no clear difference in proportion of infants who develop epilepsy post‐discharge compared with no maintenance ASM after achieving seizure control (low certainty).

1 finding from 1 review