Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,801 questions · 4,079 findings · 473 reviews

No studies found 669 · 16.4%GRADE not reported 852 · 20.9%Very low 738 · 18.1%Low 903 · 22.1%Moderate 716 · 17.6%High 201 · 4.9%

Foods fortified with zinc alone vs same foods without adding zinc

Stunting · general population of all age groups (including pregnant women) from any country, over two years of age

Foods fortified with zinc alone showed no clear difference in stunting (author defined) compared with same foods without adding zinc (low certainty).

1 finding from 1 review

Foods fortified with zinc alone vs same foods without adding zinc

Underweight · general population of all age groups (including pregnant women) from any country, over two years of age

Foods fortified with zinc alone showed no clear difference in underweight (author defined) compared with same foods without adding zinc (low certainty).

1 finding from 1 review

Foods fortified with zinc plus other micronutrients vs foods fortified with other micronutrients without zinc

Zinc deficiency (as defined by authors, depending on age and gender) · general population of all age groups (including pregnant women) from any country, over two years of age

It is very uncertain whether foods fortified with zinc plus other micronutrients changes zinc deficiency (as defined by authors, depending on age and gender) compared with foods fortified with other micronutrients without zinc (very low certainty).

1 finding from 1 review

Intervention not reported

Change in Exercise Capacity (6MWD) · Adults (>18 years) with pulmonary hypertension of varied aetiology (PAH, CTEPH and left heart disease)
1 finding from 1 review

Intervention not reported

Mortality · Adults (>18 years) with pulmonary hypertension of varied aetiology (PAH, CTEPH and left heart disease)

The intervention showed no clear difference in mortality (low certainty).

1 finding from 1 review

Intervention not reported

Improvement in WHO Functional Class · Adults (>18 years) with pulmonary hypertension of varied aetiology (PAH, CTEPH and left heart disease)

The intervention showed no clear difference in improvement in WHO Functional Class (low certainty).

1 finding from 1 review

Intervention not reported

Serious Adverse Events (Participants with one or more event) · Adults (>18 years) with pulmonary hypertension of varied aetiology (PAH, CTEPH and left heart disease)

It is very uncertain whether the intervention changes serious Adverse Events (Participants with one or more event) (very low certainty).

1 finding from 1 review

Rescue high‐frequency jet ventilation vs conventional ventilation

Overall mortality · preterm infants with severe pulmonary dysfunction

Rescue high‐frequency jet ventilation showed no clear difference in overall mortality compared with conventional ventilation (low certainty).

1 finding from 1 review

Rescue high‐frequency jet ventilation vs conventional ventilation

Mortality before cross‐over · preterm infants with severe pulmonary dysfunction

Rescue high‐frequency jet ventilation probably leads to lower mortality before cross‐over compared with conventional ventilation (moderate certainty).

1 finding from 1 review

Rescue high‐frequency jet ventilation vs conventional ventilation

Chronic lung disease · preterm infants with severe pulmonary dysfunction

Rescue high‐frequency jet ventilation showed no clear difference in chronic lung disease at 28 days of birth (CLD 28 days) compared with conventional ventilation (low certainty).

2 findings from 1 review

Rescue high‐frequency jet ventilation vs conventional ventilation

Severe intraventricular haemorrhage · preterm infants with severe pulmonary dysfunction

Rescue high‐frequency jet ventilation showed no clear difference in severe intraventricular haemorrhage (grades 3 and 4) compared with conventional ventilation (low certainty).

1 finding from 1 review