Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,092 questions · 3,199 findings · 339 reviews · Headline outcomes only

No studies found 714 · 22.3%GRADE not reported 181 · 5.7%Very low 695 · 21.7%Low 908 · 28.4%Moderate 568 · 17.8%High 133 · 4.2%

Intravenous iron vs oral iron

Ferritin (µg/L) · people with preoperative anaemia awaiting major surgery

Intravenous iron therapy may leads to higher ferritin preoperatively postintervention (ng/L) compared with oral iron therapy (low certainty).

1 finding from 1 review

Intravenous iron vs oral iron

Haemoglobin (g/dL) · people with preoperative anaemia awaiting major surgery

Intravenous iron therapy may leads to higher haemoglobin levels at end of preoperative treatment (g/dL) compared with oral iron therapy (low certainty).

2 findings from 1 review

Present‐centered therapy vs trauma‐focused cognitive behavioral therapy

Dropout from treatment (a count of participants not meeting study‐defined completion threshold) · adults aged ≥ 16 years with PTSD

Present‐centered therapy probably leads to lower treatment dropout compared with trauma‐focused cognitive behavioral therapy (moderate certainty).

1 finding from 1 review

Sublingual glucose vs oral (swallowed) glucose

Resolution of hypoglycaemia · children with hypoglycaemia associated with moderate clinical symptoms of acute malaria or moderate respiratory tract infections

It is very uncertain whether sublingual glucose changes resolution of hypoglycaemia Definition: (a) within 20 minutes (b)… compared with oral (swallowed) glucose (very low certainty).

1 finding from 1 review