Findings

What do systematic reviews say?

4,730 questions · 18,059 findings · 1,282 reviews

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No studies found 4,360 · 24.1%GRADE not reported 2,529 · 14%Very low 4,641 · 25.7%Low 4,007 · 22.2%Moderate 2,057 · 11.4%High 465 · 2.6%

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Summary of findings 2: Immunotherapies vs placebo

(4984) · adults with multiple sclerosis Interventions: immunosuppressive and immunomodulatory drugs Comparator: placebo Outcome: withdrawals due to…

1 finding from 1 review

Adverse effects of immunotherapies for multiple sclerosis: a network meta‐analysis 2023 · Cochrane Headline outcomes only
no estimate extracted
13 studies · 4688 participants
Low

Summary of findings 2: Immunotherapies vs placebo

(513) · adults with multiple sclerosis Interventions: immunosuppressive and immunomodulatory drugs Comparator: placebo Outcome: withdrawals due to…

1 finding from 1 review

Adverse effects of immunotherapies for multiple sclerosis: a network meta‐analysis 2023 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 369 participants
Very low

Summary of findings 2: Immunotherapies vs placebo

(939) · adults with multiple sclerosis Interventions: immunosuppressive and immunomodulatory drugs Comparator: placebo Outcome: withdrawals due to…

1 finding from 1 review

Adverse effects of immunotherapies for multiple sclerosis: a network meta‐analysis 2023 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 2674 participants
Low

Summary of findings 2: Immunotherapies vs placebo

(2384) · adults with multiple sclerosis Interventions: immunosuppressive and immunomodulatory drugs Comparator: placebo Outcome: withdrawals due to…

1 finding from 1 review

Adverse effects of immunotherapies for multiple sclerosis: a network meta‐analysis 2023 · Cochrane Headline outcomes only
no estimate extracted
17 studies · 3692 participants
Low

Summary of findings table ‐ Mental Health First Aid (MHFA) training vs alternative mental health literacy interventions

Individual mental health ‐ not measured · improving mental health and wellbeing

The review found no eligible studies for this question.

1 finding from 1 review

Mental Health First Aid as a tool for improving mental health and well‐being 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Mental Health First Aid (MHFA) training vs alternative mental health literacy interventions

Mental health service usage ‐ not measured · improving mental health and wellbeing

The review found no eligible studies for this question.

1 finding from 1 review

Mental Health First Aid as a tool for improving mental health and well‐being 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Mental Health First Aid (MHFA) training vs alternative mental health literacy interventions

Adverse effects of MHFA ‐ not measured · improving mental health and wellbeing

The review found no eligible studies for this question.

1 finding from 1 review

Mental Health First Aid as a tool for improving mental health and well‐being 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Mental Health First Aid (MHFA) training vs alternative interventions

Individual mental health ‐ not measured · improving mental health and wellbeing

The review found no eligible studies for this question.

1 finding from 1 review

Mental Health First Aid as a tool for improving mental health and well‐being 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Mental Health First Aid (MHFA) training vs alternative interventions

Mental health service usage ‐ not measured · improving mental health and wellbeing

The review found no eligible studies for this question.

1 finding from 1 review

Mental Health First Aid as a tool for improving mental health and well‐being 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Mental Health First Aid (MHFA) training vs alternative interventions

Adverse effects of MHFA ‐ not measured · improving mental health and wellbeing

The review found no eligible studies for this question.

1 finding from 1 review

Mental Health First Aid as a tool for improving mental health and well‐being 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Erythromycin plus nasogastric tube lavage vs no intervention/placebo plus nasogastric tube lavage

All‐cause mortality · people with acute UGIH

It is very uncertain whether erythromycin plus nasogastric tube lavage changes all‐cause mortality compared with no intervention/placebo plus nasogastric tube lavage (very low certainty).

1 finding from 1 review

Erythromycin prior to endoscopy for acute upper gastrointestinal haemorrhage 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 238 participants
Very low

Erythromycin plus nasogastric tube lavage vs no intervention/placebo plus nasogastric tube lavage

Visualisation of gastric mucosa · people with acute UGIH

1 finding from 1 review

Erythromycin prior to endoscopy for acute upper gastrointestinal haemorrhage 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 170 participants
Very low

Erythromycin plus nasogastric tube lavage vs no intervention/placebo plus nasogastric tube lavage

NSAEs · people with acute UGIH

It is very uncertain whether erythromycin plus nasogastric tube lavage changes NSAEs compared with no intervention/placebo plus nasogastric tube lavage (very low certainty).

1 finding from 1 review

Erythromycin prior to endoscopy for acute upper gastrointestinal haemorrhage 2023 · Cochrane Headline outcomes only
RD 0
6 studies · 408 participants
Very low

Erythromycin plus nasogastric tube lavage vs no intervention/placebo plus nasogastric tube lavage

Rebleeding · people with acute UGIH

It is very uncertain whether erythromycin plus nasogastric tube lavage changes rebleeding compared with no intervention/placebo plus nasogastric tube lavage (very low certainty).

1 finding from 1 review

Erythromycin prior to endoscopy for acute upper gastrointestinal haemorrhage 2023 · Cochrane Headline outcomes only
RR 1.13 [0.63, 2.02]
1 study · 169 participants
Very low

Erythromycin plus nasogastric tube lavage vs no intervention/placebo plus nasogastric tube lavage

Blood transfusion · people with acute UGIH

1 finding from 1 review

Erythromycin prior to endoscopy for acute upper gastrointestinal haemorrhage 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 180 participants
Very low

Erythromycin plus nasogastric tube lavage vs no intervention/placebo plus nasogastric tube lavage

UGIH‐related mortality · people with acute UGIH

1 finding from 1 review

Erythromycin prior to endoscopy for acute upper gastrointestinal haemorrhage 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 29 participants
Very low

Erythromycin plus nasogastric tube lavage vs no intervention/placebo plus nasogastric tube lavage

SAEs · people with acute UGIH

1 finding from 1 review

Erythromycin prior to endoscopy for acute upper gastrointestinal haemorrhage 2023 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 408 participants
Very low

Intervention not reported

Total studies: 17 RCTs Total participants: 22,819 · adolescents and adults with uncontrolled asthma, despite being on medium‐dose ICS Interventions: HD‐ICS, LD‐ICS/LABA, MD‐ICS/LAMA,…

1 finding from 1 review

Addition of long‐acting beta2 agonists or long‐acting muscarinic antagonists versus doubling the dose of inhaled… 2023 · Cochrane Headline outcomes only
no estimate extracted
17 studies · 22819 participants
GRADE not reported

Intervention not reported

LD‐ICS/LABA (Direct evidence; 0 RCTs; 0 participants) · adolescents and adults with uncontrolled asthma, despite being on medium‐dose ICS Interventions: HD‐ICS, LD‐ICS/LABA, MD‐ICS/LAMA,…

1 finding from 1 review

Addition of long‐acting beta2 agonists or long‐acting muscarinic antagonists versus doubling the dose of inhaled… 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
Low

Intervention not reported

MD‐ICS/LAMA (Direct evidence; 2 RCTs; 679 participants) · adolescents and adults with uncontrolled asthma, despite being on medium‐dose ICS Interventions: HD‐ICS, LD‐ICS/LABA, MD‐ICS/LAMA,…

1 finding from 1 review

Addition of long‐acting beta2 agonists or long‐acting muscarinic antagonists versus doubling the dose of inhaled… 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 679 participants
Low