Findings

What do systematic reviews say?

1,938 questions · 2,020 findings · 107 reviews

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No studies found 570 · 28.2%GRADE not reported 266 · 13.2%Very low 578 · 28.6%Low 462 · 22.9%Moderate 118 · 5.8%High 26 · 1.3%

Intervention not reported

High‐ versus low‐dose · children (from 1 to 18 years of age) with hypertension from primary or secondary causes

1 finding from 1 review

Pharmacological interventions for hypertension in children 2014 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 187 participants
Very low

Antihypertensive drug class vs placebo

Beta‐blocker (any dose) Mean duration of 4 weeks · children (from 1 to 18 years of age) with hypertension from primary or secondary causes

2 findings from 1 review

Pharmacological interventions for hypertension in children 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 140 participants
Very low
Pharmacological interventions for hypertension in children 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 140 participants
Very low

Intervention not reported

High‐ versus medium‐dose · children (from 1 to 18 years of age) with hypertension from primary or secondary causes

1 finding from 1 review

Pharmacological interventions for hypertension in children 2014 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 187 participants
Very low

Intervention not reported

Medium‐ versus low‐dose · children (from 1 to 18 years of age) with hypertension from primary or secondary causes

1 finding from 1 review

Pharmacological interventions for hypertension in children 2014 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 139 participants
Very low

Intervention not reported

High vs low dose Systolic blood pressure · children (from 1 to 18 years of age) with hypertension from primary or secondary causes

1 finding from 1 review

Pharmacological interventions for hypertension in children 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 141 participants
Very low

Intervention not reported

High vs low dose Diastolic blood pressure · children (from 1 to 18 years of age) with hypertension from primary or secondary causes

1 finding from 1 review

Pharmacological interventions for hypertension in children 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 141 participants
Very low

Antihypertensive drug class vs placebo

Calcium channel blocker (any dose) Mean duration of 3 weeks · children (from 1 to 18 years of age) with hypertension from primary or secondary causes

2 findings from 1 review

Pharmacological interventions for hypertension in children 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 133 participants
Very low
Pharmacological interventions for hypertension in children 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 133 participants
Very low

Antihypertensive drug class vs placebo

Beta‐blocker/thiazide combination (any dose) Mean duration of 10 weeks · children (from 1 to 18 years of age) with hypertension from primary or secondary causes

2 findings from 1 review

Pharmacological interventions for hypertension in children 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 94 participants
Very low
Pharmacological interventions for hypertension in children 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 94 participants
Very low

Intervention not reported

Angiotensin receptor blocker (high‐ versus low‐dose) · children (from 1 to 18 years of age) with hypertension from primary or secondary causes

1 finding from 1 review

Pharmacological interventions for hypertension in children 2014 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 418 participants
Low

Melatonin vs placebo

Total sleep time, next day Diaries and actigraphy. Scale from: 120 to 600. · patients with sleep disturbances caused by shift work

1 finding from 1 review

Pharmacological interventions for sleepiness and sleep disturbances caused by shift work 2014 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 263 participants
Low

Melatonin vs placebo

Total sleep time, next night; · patients with sleep disturbances caused by shift work

1 finding from 1 review

Pharmacological interventions for sleepiness and sleep disturbances caused by shift work 2014 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 234 participants
Low

Melatonin vs placebo

Sleep onset latency ‐ not reported · patients with sleep disturbances caused by shift work

1 finding from 1 review

Pharmacological interventions for sleepiness and sleep disturbances caused by shift work 2014 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 74 participants
Low

Melatonin vs placebo

Sleepiness during the night shift, postintervention; · patients with sleep disturbances caused by shift work

1 finding from 1 review

Pharmacological interventions for sleepiness and sleep disturbances caused by shift work 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 34 participants
Low

Porter 2020: armodafinil vs placebo

Sleepiness during the night shift, postintervention; · patients with sleepiness caused by shift work

1 finding from 1 review

Pharmacological interventions for sleepiness and sleep disturbances caused by shift work 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 572 participants
Moderate

Porter 2020: armodafinil vs placebo

Sleep latency MSLT. Scale from: 0 to 20 minutes. · patients with sleepiness caused by shift work

1 finding from 1 review

Pharmacological interventions for sleepiness and sleep disturbances caused by shift work 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 216 participants
Low

Modafinil vs placebo

Sleepiness during the night shift, postintervention; · patients with sleepiness caused by shift work

1 finding from 1 review

Pharmacological interventions for sleepiness and sleep disturbances caused by shift work 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 183 participants
Moderate

Modafinil vs placebo

Sleep latency MSLT. Scale from: 0 to 20 minutes. · patients with sleepiness caused by shift work

1 finding from 1 review

Pharmacological interventions for sleepiness and sleep disturbances caused by shift work 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 153 participants
Low

Job loss prevention vs control intervention

Job loss Self report by questionnaire · people with IA

1 finding from 1 review

Non‐pharmacological interventions for preventing job loss in workers with inflammatory arthritis 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 340 participants
Very low

Job loss prevention vs control intervention

Sickness absenteeism Self reported no workdays missed in past month. Scale from: 0 to 22. · people with IA

1 finding from 1 review

Non‐pharmacological interventions for preventing job loss in workers with inflammatory arthritis 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 32 participants
Very low

Job loss prevention vs control intervention

Work functioning · people with IA

1 finding from 1 review

Non‐pharmacological interventions for preventing job loss in workers with inflammatory arthritis 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 32 participants
Very low