Question · asked by 1 review

Antihypertensive drug class vs placebo: Beta‐blocker/thiazide combination (any dose) Mean duration of 10 weeks

Population
children (from 1 to 18 years of age) with hypertension from primary or secondary causes
Intervention
Antihypertensive drug class
Comparison
placebo
Outcome
Beta‐blocker/thiazide combination (any dose) Mean duration of 10 weeks

What each review found

Include earlier review versions
No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
FindingEffectStudiesGRADE certainty
Antihypertensive drug class vs placebo
Beta‐blocker/thiazide combination (any dose) Mean duration of 10 weeks · children (from 1 to 18 years of age) with hypertension from primary or secondary causes
Pharmacological interventions for hypertension in children (2014) · Cochrane Headline outcomes only
no estimate extracted1 study · 94 participantsVery low
Antihypertensive drug class vs placebo
Beta‐blocker/thiazide combination (any dose) Mean duration of 10 weeks · children (from 1 to 18 years of age) with hypertension from primary or secondary causes
Pharmacological interventions for hypertension in children (2014) · Cochrane Headline outcomes only
no estimate extracted1 study · 94 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Pharmacological interventions for hypertension in children
2014 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.