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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

1,554 questions in 140 reviews · Heart

current versions
No studies 272 · 17.5%Ungraded 44 · 2.8%Very low 329 · 21.2%Low 464 · 29.9%Moderate 319 · 20.5%High 126 · 8.1%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
[Radial] B‐mode ultrasound vs modified B‐mode ultrasound
Overall success rate · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
RR 0.93 [0.86, 1.01]2 studies · 153 participantsLow
[Radial] B‐mode ultrasound vs modified B‐mode ultrasound
Time needed for a successful procedure · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extracted2 studies · 153 participantsLow
[Axillary] B‐mode ultrasound guidance vs palpation and landmarks
Time needed for a successful procedure · adults requiring axillary artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extracted1 study · 33 participantsVery low
[Radial] B‐mode ultrasound vs modified B‐mode ultrasound
Major haematoma · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
RR 3.23 [1.37, 7.6]2 studies · 153 participantsVery low
[Radial] B‐mode ultrasound vs modified B‐mode ultrasound
Adverse events (pain) · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Radial] B‐mode ultrasound vs modified B‐mode ultrasound
Quality of life · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Radial] In‐plane B‐mode ultrasound vs out‐of‐plane B‐mode ultrasound
First‐attempt success rate · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
RR 0.85 [0.65, 1.12]8 studies · 1051 participantsVery low
[Radial] In‐plane B‐mode ultrasound vs out‐of‐plane B‐mode ultrasound
Pseudoaneurysm · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Radial] In‐plane B‐mode ultrasound vs out‐of‐plane B‐mode ultrasound
Overall success rate · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
RR 1 [0.96, 1.05]8 studies · 1051 participantsLow
[Radial] In‐plane B‐mode ultrasound vs out‐of‐plane B‐mode ultrasound
Time needed for a successful procedure · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extracted9 studies · 1134 participantsLow
[Radial] In‐plane B‐mode ultrasound vs out‐of‐plane B‐mode ultrasound
Major haematoma · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
RR 0.49 [0.22, 1.08]9 studies · 1159 participantsVery low
[Radial] In‐plane B‐mode ultrasound vs out‐of‐plane B‐mode ultrasound
Adverse events (pain) · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Radial] In‐plane B‐mode ultrasound vs out‐of‐plane B‐mode ultrasound
Quality of life · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Axillary] B‐mode ultrasound guidance vs palpation and landmarks
Major haematoma · adults requiring axillary artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
RR 0.83 [0.06, 12.22]1 study · 33 participantsVery low
[Radial] Doppler assistance vs palpation and landmarks
First‐attempt success rate · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
RR 1.01 [0.9, 1.14]2 studies · 666 participantsLow
[Radial] Doppler assistance vs palpation and landmarks
Pseudoaneurysm · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Radial] Doppler assistance vs palpation and landmarks
Overall success rate · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
RR 0.99 [0.92, 1.07]2 studies · 666 participantsLow
[Radial] Doppler assistance vs palpation and landmarks
Time needed for a successful procedure · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extracted1 study · 500 participantsModerate
[Radial] Doppler assistance vs palpation and landmarks
Major haematoma · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Radial] Doppler assistance vs palpation and landmarks
Adverse events (pain) · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Radial] Doppler assistance vs palpation and landmarks
Quality of life · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Radial] Dynamic out‐of‐plane B‐mode ultrasound vs static out‐of‐plane B‐mode ultrasound
First‐attempt success rate · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
RR 0.91 [0.67, 1.23]1 study · 131 participantsVery low
[Radial] Dynamic out‐of‐plane B‐mode ultrasound vs static out‐of‐plane B‐mode ultrasound
Pseudoaneurysm · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Radial] Dynamic out‐of‐plane B‐mode ultrasound vs static out‐of‐plane B‐mode ultrasound
Overall success rate · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
RR 1.07 [0.92, 1.25]1 study · 131 participantsVery low
[Axillary] B‐mode ultrasound guidance vs palpation and landmarks
Adverse events (pain) · adults requiring axillary artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Radial] Dynamic out‐of‐plane B‐mode ultrasound vs static out‐of‐plane B‐mode ultrasound
Time needed for a successful procedure · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extracted1 study · 131 participantsVery low
[Radial] Dynamic out‐of‐plane B‐mode ultrasound vs static out‐of‐plane B‐mode ultrasound
Major haematoma · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Radial] Dynamic out‐of‐plane B‐mode ultrasound vs static out‐of‐plane B‐mode ultrasound
Adverse events (pain) · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Radial] Dynamic out‐of‐plane B‐mode ultrasound vs static out‐of‐plane B‐mode ultrasound
Quality of life · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Radial] Oblique‐axis in‐plane B‐mode ultrasound vs long‐axis in‐plane B‐mode ultrasound
First‐attempt success rate · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
RR 1.11 [0.44, 2.79]3 studies · 275 participantsVery low
[Radial] Oblique‐axis in‐plane B‐mode ultrasound vs long‐axis in‐plane B‐mode ultrasound
Pseudoaneurysm · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Radial] Oblique‐axis in‐plane B‐mode ultrasound vs long‐axis in‐plane B‐mode ultrasound
Overall success rate · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
RR 1.27 [1.05, 1.53]2 studies · 215 participantsLow
[Radial] Oblique‐axis in‐plane B‐mode ultrasound vs long‐axis in‐plane B‐mode ultrasound
Time needed for a successful procedure · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extracted3 studies · 275 participantsVery low
[Radial] Oblique‐axis in‐plane B‐mode ultrasound vs long‐axis in‐plane B‐mode ultrasound
Major haematoma · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
RR 0.68 [0.32, 1.47]2 studies · 215 participantsVery low
[Radial] Oblique‐axis in‐plane B‐mode ultrasound vs long‐axis in‐plane B‐mode ultrasound
Adverse events (pain) · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Axillary] B‐mode ultrasound guidance vs palpation and landmarks
Quality of life · adults requiring axillary artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Radial] Oblique‐axis in‐plane B‐mode ultrasound vs long‐axis in‐plane B‐mode ultrasound
Quality of life · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Dorsalis pedis] B‐mode ultrasound guidance vs palpation and landmarks
First‐attempt success rate · adults requiring dorsalis pedis artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
RR 1.28 [0.9, 1.82]1 study · 60 participantsVery low
[Dorsalis pedis] B‐mode ultrasound guidance vs palpation and landmarks
Pseudoaneurysm · adults requiring dorsalis pedis artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
DPP4i vs placebo
Cardiovascular mortality · CVD (ASCVD, HF, or both)
Dipeptidyl peptidase‐4 inhibitors, glucagon‐like peptide 1 receptor agonists and sodium‐glucose… (2021) · Cochrane
OR 1 [0.91, 1.09]6 studies · 47968 participantsHigh
GLP‐1RA vs placebo
Cardiovascular mortality · CVD (ASCVD, HF, or both)
Dipeptidyl peptidase‐4 inhibitors, glucagon‐like peptide 1 receptor agonists and sodium‐glucose… (2021) · Cochrane
OR 0.87 [0.79, 0.95]6 studies · 46093 participantsHigh
GLP‐1RA vs placebo
Myocardial infarction (fatal or non‐fatal) · CVD (ASCVD, HF, or both)
Dipeptidyl peptidase‐4 inhibitors, glucagon‐like peptide 1 receptor agonists and sodium‐glucose… (2021) · Cochrane
OR 0.89 [0.78, 1.01]5 studies · 42910 participantsModerate
GLP‐1RA vs placebo
Stroke (fatal or non‐fatal) · CVD (ASCVD, HF, or both)
Dipeptidyl peptidase‐4 inhibitors, glucagon‐like peptide 1 receptor agonists and sodium‐glucose… (2021) · Cochrane
OR 0.87 [0.77, 0.98]5 studies · 42910 participantsHigh
GLP‐1RA vs placebo
All‐cause mortality · CVD (ASCVD, HF, or both)
Dipeptidyl peptidase‐4 inhibitors, glucagon‐like peptide 1 receptor agonists and sodium‐glucose… (2021) · Cochrane
OR 0.88 [0.82, 0.95]7 studies · 46393 participantsHigh
GLP‐1RA vs placebo
Hospitalisation for HF · CVD (ASCVD, HF, or both)
Dipeptidyl peptidase‐4 inhibitors, glucagon‐like peptide 1 receptor agonists and sodium‐glucose… (2021) · Cochrane
OR 0.95 [0.85, 1.06]6 studies · 36930 participantsHigh
GLP‐1RA vs placebo
Worsening renal function · CVD (ASCVD, HF, or both)
Dipeptidyl peptidase‐4 inhibitors, glucagon‐like peptide 1 receptor agonists and sodium‐glucose… (2021) · Cochrane
OR 0.61 [0.44, 0.84]1 study · 3297 participantsLow
GLP‐1RA vs placebo
Hypoglycaemia · CVD (ASCVD, HF, or both)
Dipeptidyl peptidase‐4 inhibitors, glucagon‐like peptide 1 receptor agonists and sodium‐glucose… (2021) · Cochrane
no estimate extracted5 studies · 37038 participantsLow
GLP‐1RA vs placebo
Pancreatitis · CVD (ASCVD, HF, or both)
Dipeptidyl peptidase‐4 inhibitors, glucagon‐like peptide 1 receptor agonists and sodium‐glucose… (2021) · Cochrane
OR 0.96 [0.68, 1.35]5 studies · 40035 participantsLow
GLP‐1RA vs placebo
Fracture · CVD (ASCVD, HF, or both)
Dipeptidyl peptidase‐4 inhibitors, glucagon‐like peptide 1 receptor agonists and sodium‐glucose… (2021) · Cochrane
no estimate extractedNRNo studies
SGLT2i vs placebo
Cardiovascular mortality · CVD (ASCVD, HF, or both)
Dipeptidyl peptidase‐4 inhibitors, glucagon‐like peptide 1 receptor agonists and sodium‐glucose… (2021) · Cochrane
OR 0.82 [0.7, 0.95]5 studies · 24962 participantsModerate