What do systematic reviews say?

492 questions · 535 findings · 56 reviews · Hypertension

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No studies found 37 · 6.9%GRADE not reported 34 · 6.4%Very low 91 · 17%Low 161 · 30.1%Moderate 136 · 25.4%High 76 · 14.2%

Intervention not reported

Androstenedione · Adult female participants with PCOS

1 finding from 1 review

Effect of atorvastatin on testosterone levels 2021 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 125 participants
Very low

Intervention not reported

DHEAS · Adult female participants with PCOS

1 finding from 1 review

Effect of atorvastatin on testosterone levels 2021 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 125 participants
Low

Intervention not reported

Acronyms and grades · Adult female participants with PCOS

The review found no eligible studies for this question.

1 finding from 1 review

Effect of atorvastatin on testosterone levels 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs Supra-gingival scaling

Percentage of bleeding on probing (BOP) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Intensive periodontal treatment (subgingival SRP with or without… led to lower bleeding on probing (BOP) compared with supra-gingival scaling; GRADE not reported.

2 findings from 1 review

Effect of periodontal treatments on blood pressure 2021 · Cochrane All outcomes
Long term · People diagnosed with periodontitis
MD -0.40 [-0.45, -0.35]
1 study
GRADE not reported
Effect of periodontal treatments on blood pressure 2021 · Cochrane All outcomes
Short term · People diagnosed with periodontitis
MD -0.42 [-0.47, -0.37]
1 study
GRADE not reported

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs No treatment (no periodontal treatment)

Endothelial function · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Periodontal treatment (subgingival SRP with or without other… showed no clear difference in endothelial function (forearm blood flow) compared with no treatment (no periodontal treatment); GRADE not reported.

1 finding from 1 review

Effect of periodontal treatments on blood pressure 2021 · Cochrane All outcomes
Long term · People diagnosed with periodontitis and other cardiovascular diseases except hypertension
MD 0.10 [-0.67, 0.87]
1 study · 48 participants
GRADE not reported

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs No treatment (no periodontal treatment)

Plasma level of IL-6 (pg/mL) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Periodontal treatment (subgingival SRP with or without other… showed no clear difference in plasma level of IL-6 (pg/mL) compared with no treatment (no periodontal treatment); GRADE not reported.

3 findings from 1 review

Effect of periodontal treatments on blood pressure 2021 · Cochrane All outcomes
Short term · People diagnosed with periodontitis
MD -0.34 [-1.06, 0.38]
1 study · 169 participants
GRADE not reported
Effect of periodontal treatments on blood pressure 2021 · Cochrane All outcomes
Long term · People diagnosed with periodontitis
MD -1.60 [-2.31, -0.89]
1 study · 168 participants
GRADE not reported
Effect of periodontal treatments on blood pressure 2021 · Cochrane All outcomes
Long term · People diagnosed with periodontitis and other cardiovascular diseases except hypertension
MD -0.90 [-2.97, 1.17]
1 study · 48 participants
GRADE not reported

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs No treatment (no periodontal treatment)

Percentage of bleeding on probing (BOP) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Periodontal treatment (subgingival SRP with or without other… led to lower bleeding on probing (BOP) compared with no treatment (no periodontal treatment); GRADE not reported.

1 finding from 1 review

Effect of periodontal treatments on blood pressure 2021 · Cochrane All outcomes
Long term · People diagnosed with periodontitis and other cardiovascular diseases except hypertension
MD -36.80 [-46.47, -27.13]
1 study · 48 participants
GRADE not reported

Intensive periodontal treatment (subgingival SRP with or without other periodontal treatment) vs No treatment (no periodontal treatment)

Heart rate · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension

Periodontal treatment (subgingival SRP with or without other… showed no clear difference in heart rate compared with no treatment (no periodontal treatment); GRADE not reported.

1 finding from 1 review

Effect of periodontal treatments on blood pressure 2021 · Cochrane All outcomes
Long term · People diagnosed with periodontitis and other cardiovascular diseases except hypertension
MD -0.70 [-6.06, 4.66]
1 study · 48 participants
GRADE not reported

Summary of findings: Low sodium intake vs high sodium intake

White population, normotensive, SBP mmHg · White population with normal or elevated blood pressure, but otherwise healthy

1 finding from 1 review

Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol,… 2020 · Cochrane Headline outcomes only
no estimate extracted
95 studies · 5982 participants
High

Summary of findings: Low sodium intake vs high sodium intake

Asian population, normotensive, DBP mmHg · Asian population with normal or elevated blood pressure, but otherwise healthy

1 finding from 1 review

Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol,… 2020 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 950 participants
Moderate

Summary of findings: Low sodium intake vs high sodium intake

Asian population, hypertensive, SBP mmHg · Asian population with normal or elevated blood pressure, but otherwise healthy

1 finding from 1 review

Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol,… 2020 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 254 participants
Low

Summary of findings: Low sodium intake vs high sodium intake

Asian population, hypertensive, DBP mmHg · Asian population with normal or elevated blood pressure, but otherwise healthy

1 finding from 1 review

Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol,… 2020 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 254 participants
Low

Summary of findings: Low sodium intake vs high sodium intake

Renin ng/ml/hour · Participants with normal or elevated blood pressure, but otherwise healthy

1 finding from 1 review

Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol,… 2020 · Cochrane Headline outcomes only
no estimate extracted
91 studies · 2904 participants
High

Summary of findings: Low sodium intake vs high sodium intake

Aldosterone pg/mL · Participants with normal or elevated blood pressure, but otherwise healthy

1 finding from 1 review

Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol,… 2020 · Cochrane Headline outcomes only
no estimate extracted
70 studies · 2506 participants
High

Summary of findings: Low sodium intake vs high sodium intake

Noradrenaline pg/mL · Participants with normal or elevated blood pressure, but otherwise healthy

1 finding from 1 review

Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol,… 2020 · Cochrane Headline outcomes only
no estimate extracted
38 studies · 878 participants
High

Summary of findings: Low sodium intake vs high sodium intake

Adrenaline pg/mL · Participants with normal or elevated blood pressure, but otherwise healthy

1 finding from 1 review

Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol,… 2020 · Cochrane Headline outcomes only
no estimate extracted
16 studies · 331 participants
Moderate

Summary of findings: Low sodium intake vs high sodium intake

Cholesterol mg/dL · Participants with normal or elevated blood pressure, but otherwise healthy

1 finding from 1 review

Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol,… 2020 · Cochrane Headline outcomes only
no estimate extracted
28 studies · 917 participants
High

Summary of findings: Low sodium intake vs high sodium intake

Trigyceride mg/dL · Participants with normal or elevated blood pressure, but otherwise healthy

1 finding from 1 review

Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol,… 2020 · Cochrane Headline outcomes only
no estimate extracted
20 studies · 712 participants
High

Summary of findings: Low sodium intake vs high sodium intake

HDL‐cholesterol · Participants with normal or elevated blood pressure, but otherwise healthy

1 finding from 1 review

Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol,… 2020 · Cochrane Headline outcomes only
no estimate extracted
20 studies · 738 participants
High

Summary of findings: Low sodium intake vs high sodium intake

White population, normotensive, DBP mmHg · White population with normal or elevated blood pressure, but otherwise healthy

1 finding from 1 review

Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol,… 2020 · Cochrane Headline outcomes only
no estimate extracted
96 studies · 6276 participants
High