Findings

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Evidence found and GRADE certainty

398 questions · 757 findings · 66 reviews · Oral Health

No studies found 20 · 2.6%GRADE not reported 574 · 75.8%Very low 39 · 5.2%Low 49 · 6.5%Moderate 53 · 7%High 22 · 2.9%

Fibre-optic transillumination (FOTI) vs Histological validation (serial sectioning, grinding, hemisection, or microradiography)

Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces

In in vitro, fibre-optic transillumination pooled specificity was 0.97 (95% CI 0.89 to 0.994) for occlusal caries at the dentin detection level; ungraded.

4 findings from 1 review
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Conventional bitewing radiography (D-speed film) vs Histological validation of dental tissues (gold standard)

Diagnostic accuracy for proximal caries detection (caries detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro)

Under in vitro conditions, conventional D-speed bitewing radiography had a pooled diagnostic odds ratio of 5.2 (95% CI 1.6, 16.8) for proximal caries detection at the caries detection level; ungraded.

4 findings from 1 review
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Visual examination (VE) vs Histological validation of dental tissues (gold standard)

Diagnostic accuracy for proximal caries detection (caries detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro)

Under in vitro conditions, visual examination had a pooled sensitivity of 0.64 (95% CI 0.42, 0.81) for proximal caries detection at the caries detection level; ungraded.

4 findings from 1 review
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Laser fluorescence (DIAGNOdent 2095) vs Cavity preparation or biopsy (operative validation)

Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) · Human permanent posterior teeth (premolars and molars) in patients, occlusal (pit-and-fissure) surfaces

In in vivo, laser fluorescence (DIAGNOdent 2095) pooled summary ROC AUC was 0.92 for occlusal caries at the dentin detection level; ungraded.

4 findings from 1 review
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Conventional bitewing radiography (D-speed film) vs Cavity preparation or biopsy (operative validation)

Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) · Human permanent posterior teeth (premolars and molars) in patients, occlusal (pit-and-fissure) surfaces

In in vivo, conventional bitewing radiography (D-speed) pooled sensitivity was 0.79 (95% CI 0.41 to 0.96) for occlusal caries at the dentin detection level; ungraded.

4 findings from 1 review
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Digital bitewing radiography, sensor-based (CCD/CMOS) vs Direct visual examination after tooth separation or bioptical cavity preparation

Diagnostic accuracy for proximal caries detection (caries detection level) · Patients with permanent posterior teeth, proximal surfaces assessed clinically (in vivo)

Under in vivo conditions, sensor-based digital bitewing radiography had a pooled specificity of 0.93 (95% CI 0.77, 0.98) for proximal caries detection at the caries detection level; ungraded.

4 findings from 1 review
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Conventional bitewing radiography, F-speed film vs Histological validation of dental tissues (gold standard)

Diagnostic accuracy for proximal caries detection (1/3 dentin detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro)

Under in vitro conditions, conventional F-speed bitewing radiography had a summary ROC AUC of 0.98 for proximal caries detection at the 1/3 dentin detection level; ungraded.

4 findings from 1 review
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Laser fluorescence (DIAGNOdent 2190/pen) vs Histological validation (serial sectioning, grinding, hemisection, or microradiography)

Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces

In in vitro, laser fluorescence pen (2190) pooled specificity was 0.77 (95% CI 0.62 to 0.88) for occlusal caries at the dentin detection level; ungraded.

4 findings from 1 review
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Laser fluorescence (DIAGNOdent 2190/pen) vs Histological validation of dental tissues (gold standard)

Diagnostic accuracy for proximal caries detection (caries detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro)

Under in vitro conditions, laser fluorescence (DIAGNOdent 2190) had a summary ROC AUC of 0.91 for proximal caries detection at the caries detection level; ungraded.

4 findings from 1 review
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Visual examination (VE) vs Histological validation of dental tissues (gold standard)

Diagnostic accuracy for proximal caries detection (1/3 dentin detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro)

Under in vitro conditions, visual examination had a pooled specificity of 0.84 (95% CI 0.76, 0.89) for proximal caries detection at the 1/3 dentin detection level; ungraded.

4 findings from 1 review
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Digital bitewing radiography, phosphor plate (PSP) vs Histological validation (serial sectioning, grinding, hemisection, or microradiography)

Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces

In in vitro, digital bitewing radiography (phosphor plates) pooled specificity was 0.95 (95% CI 0.59 to 0.995) for occlusal caries at the dentin detection level; ungraded.

4 findings from 1 review
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Visual examination (VE) vs Cavity preparation or biopsy (operative validation)

Diagnostic accuracy for occlusal caries detection at the 1/3 dentin caries detection level (Ekstrand; D0-2 versus D3-4) · Human permanent posterior teeth (premolars and molars) in patients, occlusal (pit-and-fissure) surfaces

In in vivo, visual examination pooled specificity was 0.77 (95% CI 0.67 to 0.85) for occlusal caries at the 1/3 dentin detection level; ungraded.

4 findings from 1 review
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Conventional bitewing radiography (E-speed film) vs Cavity preparation or biopsy (operative validation)

Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) · Human permanent posterior teeth (premolars and molars) in patients, occlusal (pit-and-fissure) surfaces

In in vivo, conventional bitewing radiography (E-speed) pooled diagnostic odds ratio was 127.56 (95% CI 7.38 to 2203.70) for occlusal caries at the dentin detection level; ungraded.

4 findings from 1 review
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Conventional bitewing radiography (D-speed film) vs Cavity preparation or biopsy (operative validation)

Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) · Human permanent posterior teeth (premolars and molars) in patients, occlusal (pit-and-fissure) surfaces

In in vivo, conventional bitewing radiography (D-speed) pooled sensitivity was 0.65 (95% CI 0.57 to 0.73) for occlusal caries at the caries detection level; ungraded.

4 findings from 1 review
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Conventional bitewing radiography (E-speed film) vs Cavity preparation or biopsy (operative validation)

Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) · Human permanent posterior teeth (premolars and molars) in patients, occlusal (pit-and-fissure) surfaces

In in vivo, conventional bitewing radiography (E-speed) pooled sensitivity was 0.80 (95% CI 0.71 to 0.87) for occlusal caries at the caries detection level; ungraded.

4 findings from 1 review
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Visual examination (VE) vs Histological validation (serial sectioning, grinding, hemisection, or microradiography)

Diagnostic accuracy for occlusal caries detection at the 1/3 dentin caries detection level (Ekstrand; D0-2 versus D3-4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces

In in vitro, visual examination pooled diagnostic odds ratio was 16.6 (95% CI 4.85 to 56.79) for occlusal caries at the 1/3 dentin detection level; ungraded.

4 findings from 1 review
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Digital bitewing radiography, phosphor plate (PSP) vs Histological validation of dental tissues (gold standard)

Diagnostic accuracy for proximal caries detection (dentin detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro)

Under in vitro conditions, phosphor-plate digital bitewing radiography had a summary ROC AUC of 0.92 for proximal caries detection at the dentin detection level; ungraded.

4 findings from 1 review
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Conventional bitewing radiography, F-speed film vs Histological validation (serial sectioning, grinding, hemisection, or microradiography)

Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces

In in vitro, conventional bitewing radiography (F-speed) pooled specificity was 0.97 (95% CI 0.71 to 0.998) for occlusal caries at the dentin detection level; ungraded.

4 findings from 1 review
Show 1 more finding

Conventional bitewing radiography (D-speed film) vs Histological validation (serial sectioning, grinding, hemisection, or microradiography)

Diagnostic accuracy for occlusal caries detection at the dentin caries detection level (D0-2 versus D3-4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces

In in vitro, conventional bitewing radiography (D-speed) pooled specificity was 0.73 (95% CI 0.53 to 0.87) for occlusal caries at the dentin detection level; ungraded.

4 findings from 1 review
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Visual examination (VE) vs Histological validation (serial sectioning, grinding, hemisection, or microradiography)

Diagnostic accuracy for occlusal caries detection at the caries detection level (D0 versus D1-D4) · Extracted human permanent posterior teeth (premolars and molars), occlusal (pit-and-fissure) surfaces

In in vitro, visual examination pooled summary ROC AUC was 0.59 for occlusal caries at the caries detection level; ungraded.

4 findings from 1 review
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