Findings

What do systematic reviews say?

1,520 questions · 1,575 findings · 175 reviews · Headline outcomes only

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No studies found 239 · 15.2%GRADE not reported 59 · 3.7%Very low 337 · 21.4%Low 406 · 25.8%Moderate 410 · 26%High 124 · 7.9%

Corticosteroids vs placebo

1Small sample size. · people with nerve damage (< 6 months' duration) in leprosy

1 finding from 1 review

Corticosteroids for treating nerve damage in leprosy 2016 · Cochrane Headline outcomes only
no estimate extracted
1 participants
GRADE not reported

Corticosteroids vs placebo

Improvement in sensory nerve function at 1 year · people with nerve damage (6 to 24 months' duration) in leprosy

Corticosteroids showed no clear difference in improvement in sensory nerve function at 1 year compared with placebo (moderate certainty).

1 finding from 1 review

Corticosteroids for treating nerve damage in leprosy 2016 · Cochrane Headline outcomes only
RR 0.97 [0.65, 1.45]
1 study · 71 participants
Moderate

Corticosteroids vs placebo

Improvement in motor nerve function at 1 year · people with nerve damage (6 to 24 months' duration) in leprosy

1 finding from 1 review

Corticosteroids for treating nerve damage in leprosy 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 21 participants
Low

Corticosteroids vs placebo

Number of children with clinical adverse event: vertigo · Patients with idiopathic acute vestibular dysfunction (vestibular neuritis)

Corticosteroids showed no clear difference in vertigo compared with placebo (low certainty).

1 finding from 1 review

Corticosteroids for the treatment of idiopathic acute vestibular dysfunction (vestibular neuritis) 2011 · Cochrane Headline outcomes only
RR 0.39 [0.04, 3.57]
2 studies · 60 participants
Low

Corticosteroids vs placebo

Dizziness Handicap Inventory score · Patients with idiopathic acute vestibular dysfunction (vestibular neuritis)

1 finding from 1 review

Corticosteroids for the treatment of idiopathic acute vestibular dysfunction (vestibular neuritis) 2011 · Cochrane Headline outcomes only
no estimate extracted
1 study · 30 participants
Low

Corticosteroids vs placebo

Caloric extent of recovery (improvement as a % in lateralisation of electronystagmography on caloric testing) · Patients with idiopathic acute vestibular dysfunction (vestibular neuritis)

2 findings from 1 review

Corticosteroids for the treatment of idiopathic acute vestibular dysfunction (vestibular neuritis) 2011 · Cochrane Headline outcomes only
no estimate extracted
1 study · 30 participants
Low
Corticosteroids for the treatment of idiopathic acute vestibular dysfunction (vestibular neuritis) 2011 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 89 participants
Low

Corticosteroids vs placebo

Complete caloric recovery · Patients with idiopathic acute vestibular dysfunction (vestibular neuritis)

Corticosteroids may leads to higher complete caloric recovery compared with placebo (low certainty).

2 findings from 1 review

Corticosteroids for the treatment of idiopathic acute vestibular dysfunction (vestibular neuritis) 2011 · Cochrane Headline outcomes only
RR 2.81 [1.32, 6]
2 studies · 50 participants
Low
Corticosteroids for the treatment of idiopathic acute vestibular dysfunction (vestibular neuritis) 2011 · Cochrane Headline outcomes only
RR 1.58 [0.45, 5.62]
2 studies · 89 participants
Low

Corticosteroids vs placebo

Adverse effects · Patients with idiopathic acute vestibular dysfunction (vestibular neuritis)

1 finding from 1 review

Corticosteroids for the treatment of idiopathic acute vestibular dysfunction (vestibular neuritis) 2011 · Cochrane Headline outcomes only
no estimate extracted
1 study · 73 participants
Moderate

Summary of findings for NSAIDs plus corticosteroids vs corticosteroids

Proportion of participants with best‐corrected visual acuity of 20/40 1 week · people who received phacoemulsification

The review found no eligible studies for this question.

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs versus corticosteroids for controlling inflammation after uncomplicated cataract… 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings for NSAIDs plus corticosteroids vs corticosteroids

Proportion of participants with cystoid macular edema 1 week · people who received phacoemulsification

Summary of findings for NSAIDs plus corticosteroids may leads to lower proportion of participants with cystoid macular edema 1 week compared with corticosteroids alone (low certainty).

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs versus corticosteroids for controlling inflammation after uncomplicated cataract… 2017 · Cochrane Headline outcomes only
RR 0.17 [0.03, 0.97]
2 studies · 220 participants
Low

Summary of findings for NSAIDs plus corticosteroids vs corticosteroids

Time to cessation of treatment · people who received phacoemulsification

The review found no eligible studies for this question.

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs versus corticosteroids for controlling inflammation after uncomplicated cataract… 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings for NSAIDs plus corticosteroids vs corticosteroids

Adverse events · people who received phacoemulsification

The review found no eligible studies for this question.

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs versus corticosteroids for controlling inflammation after uncomplicated cataract… 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings for NSAIDs plus corticosteroids vs corticosteroids

Economic outcomes · people who received phacoemulsification

The review found no eligible studies for this question.

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs versus corticosteroids for controlling inflammation after uncomplicated cataract… 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings for NSAIDs plus corticosteroids vs corticosteroids

Intraocular inflammation measured by anterior chamber cell and flare 1 week · people who received phacoemulsification

The review found no eligible studies for this question.

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs versus corticosteroids for controlling inflammation after uncomplicated cataract… 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings for NSAIDs plus corticosteroids vs corticosteroids

Intraocular inflammation measured by proportion of participants with corneal edema 1 week · people who received phacoemulsification

Summary of findings for NSAIDs plus corticosteroids showed no clear difference in intraocular inflammation measured by proportion of participants with… compared with corticosteroids alone (moderate certainty).

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs versus corticosteroids for controlling inflammation after uncomplicated cataract… 2017 · Cochrane Headline outcomes only
RR 1.07 [0.98, 1.16]
1 study · 138 participants
Moderate

Steroids vs no steroids (or placebo)

Pelvic pain · women after gynaecological surgery

The review found no eligible studies for this question.

1 finding from 1 review

Fluid and pharmacological agents for adhesion prevention after gynaecological surgery 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Steroids vs no steroids (or placebo)

Live birth rate · women after gynaecological surgery

Steroids (any route) may leads to lower live birth rate compared with no steroids (or placebo) (low certainty).

1 finding from 1 review

Fluid and pharmacological agents for adhesion prevention after gynaecological surgery 2020 · Cochrane Headline outcomes only
OR 0.65
2 studies · 223 participants
Low

Steroids vs no steroids (or placebo)

Incidence of adhesions at second‐look laparoscopy · women after gynaecological surgery

The review found no eligible studies for this question.

1 finding from 1 review

Fluid and pharmacological agents for adhesion prevention after gynaecological surgery 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Steroids vs no steroids (or placebo)

Mean adhesion score at second‐look laparoscopy · women after gynaecological surgery

The review found no eligible studies for this question.

1 finding from 1 review

Fluid and pharmacological agents for adhesion prevention after gynaecological surgery 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Steroids vs no steroids (or placebo)

Clinical pregnancy rate · women after gynaecological surgery

Steroids (any route) showed no clear difference in clinical pregnancy rate compared with no steroids (or placebo) (low certainty).

1 finding from 1 review

Fluid and pharmacological agents for adhesion prevention after gynaecological surgery 2020 · Cochrane Headline outcomes only
OR 1.01 [0.66, 1.55]
3 studies · 410 participants
Low