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What do systematic reviews say?

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Evidence found and GRADE certainty

170 questions · 174 findings · 17 reviews · Headline outcomes only

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No studies found 51 · 29.3%GRADE not reported 30 · 17.2%Very low 22 · 12.6%Low 38 · 21.8%Moderate 22 · 12.6%High 11 · 6.3%

Prophylactic platelet transfusion vs non prophylactic or therapeutic platelet transfusion

Mortality: secondary to bleeding · People with a haematological disorder

Prophylactic platelet transfusion showed no clear difference in mortality: Secondary to bleeding compared with non prophylactic or therapeutic platelet transfusion (low certainty).

1 finding from 1 review

Prophylactic platelet transfusion at threshold of 10,000 vs higher transfusion threshold (20,000 or 30,000)

Bleeding: Numbers of patients with at least one significant bleeding event · People with a haematological disorder

Prophylactic platelet transfusion at threshold of 10,000 showed no clear difference in bleeding: Numbers of patients with at least one significant bleeding… compared with higher transfusion threshold (20,000 or 30,000) (moderate certainty).

1 finding from 1 review

Prophylactic platelet transfusion at threshold of 10,000 vs higher transfusion threshold (20,000 or 30,000)

Mortality: secondary to bleeding · People with a haematological disorder

Prophylactic platelet transfusion at threshold of 10,000 showed no clear difference in mortality: secondary to bleeding compared with higher transfusion threshold (20,000 or 30,000) (low certainty).

1 finding from 1 review