Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

880 questions · 912 findings · 126 reviews · Headline outcomes only

No studies found 143 · 15.7%GRADE not reported 38 · 4.2%Very low 250 · 27.4%Low 253 · 27.7%Moderate 168 · 18.4%High 60 · 6.6%

Single‐dose antibiotic vs 24 hours of antibiotics

Intra‐abdominal infection · people undergoing laparotomy for penetrating abdominal trauma

It is very uncertain whether single dose of antibiotics changes intra‐abdominal infection compared with 24 hours of antibiotics (very low certainty).

1 finding from 1 review

Single‐use (sterile) catheter vs multiple‐use (clean) catheter

Number of participants with symptomatic UTI · long‐term bladder management

Single‐use (sterile) catheter showed no clear difference in number with symptomatic UTI1 compared with multiple‐use (clean) catheter (low certainty).

1 finding from 1 review

Single component intervention vs control

Adherence to pharmacotherapy: number of people completing treatment · COPD

Single component intervention showed no clear difference in adherence to pharmacotherapy: number of people completing treatment compared with control (low certainty).

1 finding from 1 review

Single component intervention vs control

Exacerbations (number of people experiencing ≥ 1 exacerbations) · COPD

It is very uncertain whether single component intervention changes exacerbations: number of people experiencing exacerbations compared with control (very low certainty).

1 finding from 1 review

Single component intervention vs control

Adverse events: number of people experiencing adverse events (all cause or COPD‐related), serious adverse events, mortality · COPD

It is very uncertain whether single component intervention changes adverse events: number of people experiencing adverse events (all… compared with control (very low certainty).

1 finding from 1 review

Procedures: single‐step doffing vs Centers

Contamination with fluorescent · Preventing highly infectious diseases due to exposure to contaminated body fluids in healthcare staff

It is very uncertain whether procedures: single‐step doffing changes fluorescent contamination compared with centers (very low certainty).

1 finding from 1 review

Procedures: single‐step doffing vs Centers

Bacterial contamination · Preventing highly infectious diseases due to exposure to contaminated body fluids in healthcare staff

It is very uncertain whether procedures: single‐step doffing changes bacterial contamination compared with centers (very low certainty).

1 finding from 1 review