Honey vs silver sulfadiazine
Quality of Life6 · people with burns
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Findings
What do systematic reviews say?
214 questions · 250 findings · 24 reviews
No studies found 50 · 20%GRADE not reported 112 · 44.8%Very low 42 · 16.8%Low 24 · 9.6%Moderate 17 · 6.8%High 5 · 2%
SDF (given at a particular frequency, concentration, or duration) vs SDF (given at a different frequency, concentration, or duration)
Caries arrest · Children and adults (with or without carious lesions)
1 finding from 1 review
- Topical silver diamine fluoride (SDF) for preventing and managing dental caries in children and adults 2024 · Cochrane All outcomes12 to 30 months · Primary dentitionIn 1 study (45 children), 4 applications of 38% SDF at 1-monthly intervals resulted in fewer surfaces with active caries compared with 2 applications at 6-monthly intervals (MD 1.04 surfaces, 95% CI 0.23 to 1.85), and…4 studies · 1360 participantsVery low
SDF (given at a particular frequency, concentration, or duration) vs SDF (given at a different frequency, concentration, or duration)
Aesthetics · Children and adults (with or without carious lesions)
1 finding from 1 review
- Topical silver diamine fluoride (SDF) for preventing and managing dental caries in children and adults 2024 · Cochrane All outcomes24 months · Children1 study (119 children) reported that 45% parents were satisfied with child's dental appearance (data not reported by study group)1 study · 119 participantsVery low
SDF (given at a particular frequency, concentration, or duration) vs SDF (given at a different frequency, concentration, or duration)
Secondary prevention of caries · Children and adults (with or without carious lesions)
It is very uncertain whether SDF (given at a particular frequency, concentration, or duration) changes secondary prevention of caries compared with SDF (given at a different frequency, concentration, or duration) (very low certainty).
1 finding from 1 review
- Topical silver diamine fluoride (SDF) for preventing and managing dental caries in children and adults 2024 · Cochrane All outcomes30 months · Primary dentitionMD -0.10 [-0.61, 0.41]1 study · 203 participantsVery low
SDF (given at a particular frequency, concentration, or duration) vs SDF (given at a different frequency, concentration, or duration)
Primary caries prevention · Children and adults (with or without carious lesions)
The review found no eligible studies for this question.
1 finding from 1 review
- Topical silver diamine fluoride (SDF) for preventing and managing dental caries in children and adults 2024 · Cochrane All outcomesNo studies reported data for this outcome0 studiesNo studies found
SDF (given at a particular frequency, concentration, or duration) vs SDF (given at a different frequency, concentration, or duration)
Dental pain or sensitivity · Children and adults (with or without carious lesions)
The review found no eligible studies for this question.
1 finding from 1 review
- Topical silver diamine fluoride (SDF) for preventing and managing dental caries in children and adults 2024 · Cochrane All outcomesNo studies reported data for this outcome0 studiesNo studies found
SDF (given at a particular frequency, concentration, or duration) vs SDF (given at a different frequency, concentration, or duration)
Adverse effects · Children and adults (with or without carious lesions)
1 finding from 1 review
- Topical silver diamine fluoride (SDF) for preventing and managing dental caries in children and adults 2024 · Cochrane All outcomes24 to 30 months · Children1 study (203 children) reported that black or brown staining on treated lesions was commonly found in both groups, with little or no difference according to whether SDF treatment was given in 3 applications at…3 studies · 1121 participantsVery low
38% SDF (indirect pulp capping) vs Resin-modified glass ionomer cement (RMGIC)
Restoration color, marginal staining and luster (esthetics) · Children with deep occlusal caries in young permanent first molars (indirect pulp capping)
RMGIC gave significantly better restoration esthetics than SDF, which caused black staining (p=0.03; ungraded).
1 finding from 1 review
- A systematic review on the effect of silver diamine fluoride for management of dental caries in permanent teeth. 2023 All outcomes12 months · University dental clinic (children) · Baraka 2022Baraka et al. (2022): significant differences in restoration color, marginal staining and luster favoring RMGIC over both SDF groups (p=0.03); SDF caused black staining that darkened over time.1 study · 49 participantsGRADE not reported
38% silver diamine fluoride vs Atraumatic restorative treatment (ART)
Caries/restoration status in permanent molars · Children with dental caries in permanent (first) molars
SDF gave significantly better caries/restoration outcomes than ART over 9 months in children's permanent molars (p=0.004; ungraded).
1 finding from 1 review
- A systematic review on the effect of silver diamine fluoride for management of dental caries in permanent teeth. 2023 All outcomes9 months · School-based (children) · Satyarup 2022 (school setting, India)Satyarup et al. (2022): 38% SDF vs ART; SDF group 5.6% carious teeth with partly lost restorations vs ART 16.7% carious with partly lost and 8.9% carious with completely lost restorations (p=0.004, favoring SDF).1 study · 190 participantsGRADE not reported
38% SDF plus oral health education vs oral health instruction plus tonic water
new root-surface carious lesions or restorations · community-dwelling older adults with root caries
SDF had a 62% preventative fraction; no pooled estimate or GRADE rating was reported.
1 finding from 1 review
- A systematic review on the effect of silver diamine fluoride for management of dental caries in permanent teeth. 2023 All outcomes30 months · Hong KongPreventative fraction (%) 621 study · 323 participantsGRADE not reported
Sodium fluoride (5% NaF, one-time [Mauro] or every 6 months [Liu]) vs Control (water or unspecified)
New coronal caries in permanent molars (caries prevention) · Children with dental caries in permanent (first) molars
NaF gave a 48% prevented fraction (fissure site) vs water (p<0.002; ungraded).
3 findings from 1 review
- A systematic review on the effect of silver diamine fluoride for management of dental caries in permanent teeth. 2023 All outcomes24 months · School-based (children) · Liu 2012 (5% NaF, fissure site)Prevented Fraction 481 study · 501 participantsGRADE not reported
- A systematic review on the effect of silver diamine fluoride for management of dental caries in permanent teeth. 2023 All outcomes12 months · School-based (children) · Mauro 2004 (5% NaF one-time)Prevented Fraction 471 study · 141 participantsGRADE not reported
- A systematic review on the effect of silver diamine fluoride for management of dental caries in permanent teeth. 2023 All outcomes24 months · School-based (children) · Liu 2012 (5% NaF, tooth level)Prevented Fraction 411 study · 501 participantsGRADE not reported
38% SDF plus potassium iodide and oral health instruction vs oral health instruction plus tonic water
new root-surface carious lesions or restorations · community-dwelling older adults with root caries
SDF plus potassium iodide had a 52% preventative fraction; no pooled estimate or GRADE rating was reported.
1 finding from 1 review
- A systematic review on the effect of silver diamine fluoride for management of dental caries in permanent teeth. 2023 All outcomes30 months · Hong KongPreventative fraction (%) 521 study · 323 participantsGRADE not reported
Atraumatic restorative treatment (ART) sealant (one-time) vs no treatment
New coronal caries in permanent first molars (caries prevention) · Children with dental caries in permanent (first) molars
ART within a brushing programme significantly reduced caries vs control (p<0.01; ungraded).
2 findings from 1 review
- A systematic review on the effect of silver diamine fluoride for management of dental caries in permanent teeth. 2023 All outcomes18 months · School-based (children) · Monse 2012 (ART one-time, with brushing programme)Mean new caries increment (surfaces) 0.011 study · 1016 participantsGRADE not reported
- A systematic review on the effect of silver diamine fluoride for management of dental caries in permanent teeth. 2023 All outcomes18 months · School-based (children) · Monse 2012 (ART one-time, no brushing programme)Mean new caries increment (surfaces) 0.061 study · 1016 participantsGRADE not reported
2.26% ammonium bifluoride (one-time) vs Control (details reported as unavailable)
New coronal caries in permanent first molars (caries prevention) · Children with dental caries in permanent (first) molars
One-time ammonium bifluoride gave a 56% prevented fraction, similar to SDF (57%) (single study; ungraded).
1 finding from 1 review
- A systematic review on the effect of silver diamine fluoride for management of dental caries in permanent teeth. 2023 All outcomes12 months · School-based (children) · Mauro 2004Prevented Fraction 561 study · 141 participantsGRADE not reported
38% SDF (one-time application) vs inactive control
New coronal carious lesions or fillings on permanent (first) molars (caries prevention) · Children with dental caries in permanent (first) molars
One-time SDF within a brushing programme did not significantly reduce caries vs control (p>0.05; ungraded).
2 findings from 1 review
- A systematic review on the effect of silver diamine fluoride for management of dental caries in permanent teeth. 2023 All outcomes18 months · School-based (children) · Monse 2012 (SDF one-time, with toothbrushing programme)Mean new caries increment (surfaces) 0.091 study · 1016 participantsGRADE not reported
- A systematic review on the effect of silver diamine fluoride for management of dental caries in permanent teeth. 2023 All outcomes18 months · School-based (children) · Monse 2012 (SDF one-time, no toothbrushing programme; Philippines)Mean new caries increment (surfaces) 0.121 study · 1016 participantsGRADE not reported
38% SDF (indirect pulp capping) vs Resin-modified glass ionomer cement (RMGIC)
Secondary prevention of caries · children with deep occlusal carious lesions in permanent molars
No significant difference in secondary caries prevention was reported; no effect estimate or GRADE rating was reported.
1 finding from 1 review
- A systematic review on the effect of silver diamine fluoride for management of dental caries in permanent teeth. 2023 All outcomes12 months · Alexandria Egyptno estimate extracted1 study · 49 participantsGRADE not reported
38% SDF (indirect pulp capping under resin composite) vs Resin-modified glass ionomer cement (RMGIC)
Secondary caries prevention in young permanent first molars · Children with deep occlusal caries in young permanent first molars (indirect pulp capping)
SDF and RMGIC did not differ significantly for secondary caries prevention in young permanent molars (no events; p>0.05; ungraded).
1 finding from 1 review
- A systematic review on the effect of silver diamine fluoride for management of dental caries in permanent teeth. 2023 All outcomes12 months · University dental clinic (children) · Baraka 2022 (indirect pulp capping, Egypt)Baraka et al. (2022): no significant difference in secondary caries prevention between 38% SDF and RMGIC (no secondary caries in either group through 12 months; p=0.63 at 12 months; overall p=0.26).1 study · 49 participantsGRADE not reported
38% SDF (every 6 months) vs no treatment
new active or inactive carious lesions · Children with dental caries in permanent (first) molars
SDF had a 72% preventative fraction; no pooled estimate or GRADE rating was reported.
1 finding from 1 review
- A systematic review on the effect of silver diamine fluoride for management of dental caries in permanent teeth. 2023 All outcomes36 months · Santiago de Cuba CubaPreventative fraction (%) 721 study · 452 participantsGRADE not reported
38% SDF plus potassium iodide (KI) (indirect pulp capping) vs Resin-modified glass ionomer cement (RMGIC)
Secondary prevention of caries · children with deep occlusal carious lesions in permanent molars
No significant difference in secondary caries prevention was reported; no effect estimate or GRADE rating was reported.
1 finding from 1 review
- A systematic review on the effect of silver diamine fluoride for management of dental caries in permanent teeth. 2023 All outcomes12 months · Alexandria EgyptSDF+KI 2 (8%) vs RMGIC 0 (0%); p=0.63 (NS), 12 months1 study · 49 participantsGRADE not reported
38% SDF every 12 months vs water every 12 months
new carious lesions or fillings at tooth level · children with caries in permanent molars
SDF had a 41% preventative fraction at tooth level; no pooled estimate or GRADE rating was reported.
1 finding from 1 review
- A systematic review on the effect of silver diamine fluoride for management of dental caries in permanent teeth. 2023 All outcomes24 months · Guangzhou ChinaPreventative fraction (%) 411 study · 501 participantsGRADE not reported