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Evidence found and GRADE certainty

327 questions · 337 findings · 47 reviews · Headline outcomes only

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No studies found 69 · 20.5%GRADE not reported 35 · 10.4%Very low 49 · 14.5%Low 73 · 21.7%Moderate 63 · 18.7%High 48 · 14.2%

Mammography in combination with breast ultrasonography vs mammography alone

False‐negative rate in women with dense breasts · breast cancer screening in women at average risk with dense breasts

Mammography in combination with breast ultrasonography probably leads to lower false‐negative rate in women with dense breasts compared with mammography alone (moderate certainty).

1 finding from 1 review

Mammography in combination with breast ultrasonography vs mammography alone

Biopsy rate in women with dense breasts · breast cancer screening in women at average risk with dense breasts

Mammography in combination with breast ultrasonography leads to higher biopsy rate in women with dense breasts compared with mammography alone (high certainty).

1 finding from 1 review

Mammography in combination with breast ultrasonography vs mammography alone

Incremental cancer detection for women with non‐dense breasts: cohort studies · breast cancer screening (non‐dense breasts)

Mammography in combination with breast ultrasonography probably leads to higher incremental cancer detection for women with non‐dense breasts: RCT compared with mammography alone (moderate certainty).

2 findings from 1 review

Mammography in combination with breast ultrasonography vs mammography alone

Interval cancer · breast cancer screening (non‐dense breasts)

Mammography in combination with breast ultrasonography showed no clear difference in interval cancer compared with mammography alone (high certainty).

1 finding from 1 review

Mammography in combination with breast ultrasonography vs mammography alone

False‐positive rate in women with non‐dense breasts · breast cancer screening (non‐dense breasts)

Mammography in combination with breast ultrasonography leads to higher false‐positive rate in women with non‐dense breasts compared with mammography alone (high certainty).

1 finding from 1 review

Mammography in combination with breast ultrasonography vs mammography alone

False‐negative rate in women with non‐dense breasts · breast cancer screening (non‐dense breasts)

Mammography in combination with breast ultrasonography probably leads to lower false‐negative rate in women with non‐dense breasts compared with mammography alone (moderate certainty).

1 finding from 1 review

Mammography in combination with breast ultrasonography vs mammography alone

Biopsy rate in women with non‐dense breasts · breast cancer screening (non‐dense breasts)

Mammography in combination with breast ultrasonography leads to higher biopsy rate in women with non‐dense breasts compared with mammography alone (high certainty).

1 finding from 1 review