Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

749 questions · 769 findings · 63 reviews · Headline outcomes only

No studies found 202 · 26.3%GRADE not reported 31 · 4%Very low 172 · 22.4%Low 211 · 27.4%Moderate 106 · 13.8%High 47 · 6.1%

Prophylactic intravenous antibiotics administered before cesarean incision vs after neonatal umbilical cord clamping

Maternal UTI/cystitis/pyelonephritis · women undergoing caesarean section

Prophylactic intravenous antibiotics administered before cesarean… showed no clear difference in maternal UTI/cystitis/pyelonephritis compared with after neonatal umbilical cord clamping (moderate certainty).

1 finding from 1 review

Prophylactic intravenous antibiotics administered before cesarean incision vs after neonatal umbilical cord clamping

Maternal respiratory infection (pneumonia) · women undergoing caesarean section

Prophylactic intravenous antibiotics administered before cesarean… showed no clear difference in maternal respiratory infection (pneumonia) compared with after neonatal umbilical cord clamping (low certainty).

1 finding from 1 review

Prophylactic intravenous antibiotics administered before cesarean incision vs after neonatal umbilical cord clamping

Neonatal sepsis · women undergoing caesarean section

Prophylactic intravenous antibiotics administered before cesarean… showed no clear difference in neonatal sepsis compared with after neonatal umbilical cord clamping (moderate certainty).

1 finding from 1 review

Prophylactic intravenous antibiotics administered before cesarean incision vs after neonatal umbilical cord clamping

Admission to neonatal intensive care unit · women undergoing caesarean section

Prophylactic intravenous antibiotics administered before cesarean… showed no clear difference in neonatal ICU admission compared with after neonatal umbilical cord clamping (high certainty).

1 finding from 1 review

FXIII: Prophylactic trials: intervention vs inactive control

Arterial thromboembolic events Post‐operatively · the prevention and treatment of bleeding in patients without haemophilia

FXIII: Prophylactic trials: intervention showed no clear difference in arterial thromboembolic events Up to 5 to 7 weeks post‐operatively compared with inactive control (low certainty).

3 findings from 1 review

FXIII: Prophylactic trials: intervention vs inactive control

Venous thromboembolic events · the prevention and treatment of bleeding in patients without haemophilia

FXIII: Prophylactic trials: intervention showed no clear difference in venous thromboembolic events ‐ Up to 5 to 7 weeks post‐operatively compared with inactive control (low certainty).

2 findings from 1 review

FXIII: Prophylactic trials: intervention vs inactive control

Venous thromboembolic events Up to 30 days post‐operatively · the prevention and treatment of bleeding in patients without haemophilia

FXIII: Prophylactic trials: intervention showed no clear difference in venous thromboembolic events Up to 30 days post‐operatively compared with inactive control (low certainty).

1 finding from 1 review

Prophylactic administration of paracetamol vs placebo or no intervention

Failure of PDA closure after first course of treatment (assessed by post‐treatment ECHO) · preterm infants with PDA

Prophylactic administration of paracetamol may leads to lower failure of PDA closure after first course (assessed by… compared with placebo or no intervention (low certainty).

1 finding from 1 review

Prophylactic administration of paracetamol vs placebo or no intervention

All‐cause mortality during hospital stay · preterm infants with PDA

Prophylactic administration of paracetamol showed no clear difference in all‐cause mortality during initial hospital stay (by clinical… compared with placebo or no intervention (low certainty).

1 finding from 1 review

Prophylactic perindopril (2 mg to 4 mg daily) vs placebo

Change in cardiac function: number of patients with EF < 45% · boys with DMD, normal cardiac examination and LVEF > 55% at baseline

It is very uncertain whether prophylactic perindopril (2 mg to 4 mg daily) changes change in cardiac function: number of patients with EF < 45% compared with placebo (very low certainty).

1 finding from 1 review

Prophylactic perindopril (2 mg to 4 mg daily) vs placebo

Adverse events · boys with DMD, normal cardiac examination and LVEF > 55% at baseline

Prophylactic perindopril (2 mg to 4 mg daily) showed no clear difference in adverse events compared with placebo (low certainty).

1 finding from 1 review