FXIII: Prophylactic trials: intervention vs inactive control: Arterial thromboembolic events Post‐operatively
FXIII: Prophylactic trials: intervention showed no clear difference in arterial thromboembolic events Up to 5 to 7 weeks post‐operatively compared with inactive control (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
FXIII: Prophylactic trials: intervention vs inactive control Arterial thromboembolic events Up to 5 to 7 weeks post‐operatively · the prevention and treatment of bleeding in patients without haemophilia FXIII: Prophylactic trials: intervention showed no clear difference in arterial thromboembolic events Up to 5 to 7 weeks post‐operatively compared with inactive control (low certainty). Pro‐coagulant haemostatic factors for the prevention and treatment of bleeding in people without haemophilia (2018) · Cochrane Headline outcomes only | RR 0.67 [0.28, 1.62] | 2 studies · 282 participants | Low |
FXIII: Prophylactic trials: intervention vs inactive control Arterial thromboembolic events Up to 30 days post‐operatively · the prevention and treatment of bleeding in patients without haemophilia FXIII: Prophylactic trials: intervention showed no clear difference in arterial thromboembolic events Up to 30 days post‐operatively compared with inactive control (low certainty). Pro‐coagulant haemostatic factors for the prevention and treatment of bleeding in people without haemophilia (2018) · Cochrane Headline outcomes only | RR 3 [0.14, 66.53] | 1 study · 22 participants | Low |
FXIII: Prophylactic trials: intervention vs inactive control Arterial thromboembolic events Post‐operatively · the prevention and treatment of bleeding in patients without haemophilia It is very uncertain whether FXIII: Prophylactic trials: intervention changes arterial thromboembolic events Post‐operatively compared with inactive control (very low certainty). Pro‐coagulant haemostatic factors for the prevention and treatment of bleeding in people without haemophilia (2018) · Cochrane Headline outcomes only | RR 0.2 [0.01, 3.97] | 1 study · 50 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Pro‐coagulant haemostatic factors for the prevention and treatment of bleeding in people without haemophilia 2018 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.