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What do systematic reviews say?

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Evidence found and GRADE certainty

2,289 questions · 2,331 findings · 195 reviews · Pregnancy and Childbirth

No studies found 480 · 20.6%GRADE not reported 288 · 12.4%Very low 467 · 20%Low 630 · 27%Moderate 338 · 14.5%High 128 · 5.5%

Any intervention to prevent violence (all interventions) vs usual care

Partner abuse: abuse score in the first 3 months postpartum (Conflict Tactics Score*) The CTS is a 19‐item self‐report scale listing behaviours that the respondent’s partner might use in conflicts. Women report the frequency of partner behaviours ... · pregnant women
1 finding from 1 review

Outcomes for all interventions for smoking cessation in pregnancy vs control: subgrouped by main intervention strategy (comparison 20)

Birthweight < 2500 (g) · Pregnant women who smoke

Outcomes for all interventions for smoking cessation in pregnancy leads to lower low birthweight (under 2500 g) compared with control: subgrouped by main intervention strategy (comparison 20) (high certainty).

1 finding from 1 review

Outcomes for all interventions for smoking cessation in pregnancy vs control: subgrouped by main intervention strategy (comparison 20)

Mean birthweight · Pregnant women who smoke

Outcomes for all interventions for smoking cessation in pregnancy showed no clear difference in mean birthweight (g) compared with control: subgrouped by main intervention strategy (comparison 20) (high certainty).

1 finding from 1 review

Outcomes for all interventions for smoking cessation in pregnancy vs control: subgrouped by main intervention strategy (comparison 20)

Stillbirth · Pregnant women who smoke

Outcomes for all interventions for smoking cessation in pregnancy showed no clear difference in stillbirths compared with control: subgrouped by main intervention strategy (comparison 20) (high certainty).

1 finding from 1 review

Outcomes for all interventions for smoking cessation in pregnancy vs control: subgrouped by main intervention strategy (comparison 20)

Admission to NICU (primary outcome)№ of participants: 204(1 RCT) · Pregnant women who smoke

Outcomes for all interventions for smoking cessation in pregnancy leads to lower NICU admissions compared with control: subgrouped by main intervention strategy (comparison 20) (high certainty).

1 finding from 1 review

Prevention of eclampsia: IV maintenance vs a serial IV bolus regimen

Death of the baby before discharge: perinatal death · women with pre‐eclampsia

It is very uncertain whether prevention of eclampsia: maintenance regimen by continuous infusion changes death of the baby before discharge: perinatal death compared with a serial IV bolus regimen (very low certainty).

1 finding from 1 review

Prevention of eclampsia: IV maintenance vs a serial IV bolus regimen

Other neonatal morbidity: neonatal respiratory morbidity · women with pre‐eclampsia

It is very uncertain whether prevention of eclampsia: maintenance regimen by continuous infusion changes other neonatal morbidity: neonatal respiratory morbidity compared with a serial IV bolus regimen (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Vitamin B12 supplementation vs no supplementation or placebo

Preterm birth · pregnant women

Summary of findings table ‐ Vitamin B12 supplementation showed no clear difference in preterm birth (< 37 weeks) compared with placebo/no vitamin B12 supplementation (low certainty).

1 finding from 1 review