Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

183 questions · 187 findings · 19 reviews · Infectious Diseases

No studies found 27 · 14.4%GRADE not reported 12 · 6.4%Very low 58 · 31%Low 31 · 16.6%Moderate 34 · 18.2%High 25 · 13.4%

Intervention not reported

Index test · children with close tuberculosis contacts Index tests: groups of multiple symptoms Role: an initial test Threshold for index tests: any 1…

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Specificities 99% and 100% · children evaluated in inpatient or outpatient settings Index tests: Xpert MTB/RIF Role: an initial test Threshold for index tests: an…
1 finding from 1 review

Intervention not reported

≥ 1 of cough, fever, or poor weight gain · children with close tuberculosis contacts Index tests: groups of multiple symptoms Role: an initial test Threshold for index tests: any 1…
1 finding from 1 review

Intervention not reported

≥ 1 of cough, fever, or decreased playfulness · children with close tuberculosis contacts Index tests: groups of multiple symptoms Role: an initial test Threshold for index tests: any 1…
1 finding from 1 review

Intervention not reported

≥ 1 of cough, fever, poor weight gain, or tuberculosis close contact (WHO 4‐symptom symptom screen) · children with close tuberculosis contacts Index tests: groups of multiple symptoms Role: an initial test Threshold for index tests: any 1…
1 finding from 1 review

Intervention not reported

Estimation (95% Cl) · children with close tuberculosis contacts Index test: abnormal chest radiography Role: an initial test Threshold for index tests: author…

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Pooled sensitivity 87% (75% to 93%) · children with close tuberculosis contacts Index test: abnormal chest radiography Role: an initial test Threshold for index tests: author…
1 finding from 1 review

Intervention not reported

Pooled specificity 99% (68% to 100%) · children with close tuberculosis contacts Index test: abnormal chest radiography Role: an initial test Threshold for index tests: author…
1 finding from 1 review

Intervention not reported

Estimations · children evaluated in inpatient or outpatient settings Index tests: Xpert MTB/RIF Role: an initial test Threshold for index tests: an…

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Sensitivities 43% and 100% · children evaluated in inpatient or outpatient settings Index tests: Xpert MTB/RIF Role: an initial test Threshold for index tests: an…
1 finding from 1 review