Findings

What do systematic reviews say?

166 questions · 178 findings · 15 reviews

No studies found 52 · 29.2%GRADE not reported 1 · 0.6%Very low 44 · 24.7%Low 56 · 31.5%Moderate 24 · 13.5%High 1 · 0.6%

OHSS · women undergoing assisted reproduction

Combined oral contraceptive pill showed no clear difference in OHSS rate (COCP + Ant vs Ant) compared with no pretreatment (low certainty).

2 findings from 1 review

Live birth ‐ Clomiphene citrate 5 days versus clomiphene citrate 10 days · ovulation induction in polycystic ovarian syndrome

The intervention may leads to lower live birth ‐ Clomiphene citrate 5 days versus clomiphene citrate 10… (low certainty).

1 finding from 1 review

Clomiphene and other antioestrogens for ovulation induction in polycystic ovarian syndrome 2016 · Cochrane Headline outcomes only
OR 0.1 [0.02, 0.45]
1 study · 220 participants
Low

Clinical pregnancy ‐ Clomiphene citrate 5 days versus clomiphene citrate 10 days · ovulation induction in polycystic ovarian syndrome

The intervention may leads to lower clinical pregnancy ‐ Clomiphene citrate 5 days versus clomiphene… (low certainty).

1 finding from 1 review

Clomiphene and other antioestrogens for ovulation induction in polycystic ovarian syndrome 2016 · Cochrane Headline outcomes only
OR 0.18 [0.06, 0.55]
1 study · 220 participants
Low

Multiple pregnancy ‐ Clomiphene citrate 5 days versus clomiphene citrate 10 days · ovulation induction in polycystic ovarian syndrome

It is very uncertain whether the intervention changes multiple pregnancy ‐ Clomiphene citrate 5 days versus clomiphene… (very low certainty).

1 finding from 1 review

Clomiphene and other antioestrogens for ovulation induction in polycystic ovarian syndrome 2016 · Cochrane Headline outcomes only
OR 0.33 [0.03, 3.2]
1 study · 220 participants
Very low

Miscarriage rate ‐ Early versus late clomiphene citrate · ovulation induction in polycystic ovarian syndrome

It is very uncertain whether the intervention changes miscarriage rate ‐ Early versus late clomiphene citrate (very low certainty).

1 finding from 1 review

Clomiphene and other antioestrogens for ovulation induction in polycystic ovarian syndrome 2016 · Cochrane Headline outcomes only
OR 1.25 [0.27, 5.7]
1 study · 212 participants
Very low

Clinical pregnancy ‐ Early versus late clomiphene citrate · ovulation induction in polycystic ovarian syndrome

The intervention may leads to higher clinical pregnancy ‐ Early versus late clomiphene citrate (low certainty).

1 finding from 1 review

Clomiphene and other antioestrogens for ovulation induction in polycystic ovarian syndrome 2016 · Cochrane Headline outcomes only
OR 2.81 [1.02, 7.75]
1 study · 78 participants
Low