Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

521 questions · 544 findings · 62 reviews

No studies found 153 · 28.1%GRADE not reported 29 · 5.3%Very low 134 · 24.6%Low 123 · 22.6%Moderate 80 · 14.7%High 25 · 4.6%

Decompressive craniectomy vs medical treatment

Mortality at 6 months · patients > 12 months of age with a severe traumatic brain injury and in a coma (post‐resuscitation GOS score ≤ 8 points) with raised,…

Decompressive craniectomy probably leads to lower mortality at 6 months compared with medical treatment only (moderate certainty).

1 finding from 1 review

Decompressive craniectomy vs medical treatment

Mortality at 12 months · patients > 12 months of age with a severe traumatic brain injury and in a coma (post‐resuscitation GOS score ≤ 8 points) with raised,…

Decompressive craniectomy leads to lower mortality at 12 months compared with medical treatment only (high certainty).

1 finding from 1 review

Decompressive craniectomy vs medical treatment

'Unfavorable outcome' as per original Cochrane protocol at 6 months · patients > 12 months of age with a severe traumatic brain injury and in a coma (post‐resuscitation GOS score ≤ 8 points) with raised,…

Decompressive craniectomy may leads to higher 'Unfavorable outcome' as per original Cochrane protocol at 6 months compared with medical treatment only (low certainty).

1 finding from 1 review

Decompressive craniectomy vs medical treatment

'Unfavorable outcome' as per original Cochrane protocol ‐ at 12 months · patients > 12 months of age with a severe traumatic brain injury and in a coma (post‐resuscitation GOS score ≤ 8 points) with raised,…

Decompressive craniectomy showed no clear difference in 'Unfavorable outcome' as per original Cochrane protocol ‐ at 12 months compared with medical treatment only (high certainty).

1 finding from 1 review

Decompressive craniectomy vs medical treatment

Changes in ICP from randomization up to 48 h · patients > 12 months of age with a severe traumatic brain injury and in a coma (post‐resuscitation GOS score ≤ 8 points) with raised,…

Decompressive craniectomy showed no clear difference in changes in ICP from randomization up to 48 h compared with medical treatment only (moderate certainty).

1 finding from 1 review

Sedation

Outcome not reported · Medically compromised children (ASA III+) or children with learning/behavioural difficulties needing dental treatment

The review found no eligible studies for this question.

1 finding from 1 review
  • 'Some of the techniques described may be useful in the management of medically compromised patients, but at present there are no studies carried out in these groups.' (Discussion) Explicit evidence gap.
    0 studies
    No studies found

Surgery vs oral medication

Overall satisfaction with treatment At 5 years · women with heavy menstrual bleeding

It is very uncertain whether surgery changes overall satisfaction with treatment At 5 years compared with oral medication (very low certainty).

1 finding from 1 review

Transmyocardial laser revascularization vs medical treatment

Angina reduction ‐ NYHA scale Decrease in two angina classes or more · patients with refractory angina

Transmyocardial laser revascularization may leads to higher angina reduction Decrease in two angina classes or more compared with medical treatment (low certainty).

2 findings from 1 review

Transmyocardial laser revascularization vs medical treatment

Angina reduction ‐ CCS score Decrease in two angina classes or more · patients with refractory angina

Transmyocardial laser revascularization may leads to higher angina reduction ‐ CCS score Decrease in two angina classes or more compared with medical treatment (low certainty).

1 finding from 1 review