Serious adverse events · people with sickle cell disease
Hydroxyurea showed no clear difference in serious adverse events compared with placebo (low certainty).
1 finding from 1 review
All‐cause mortality · people with sickle cell disease
Quality of life · people with sickle cell disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Reduction or prevention of kidney disease progression · people with sickle cell disease
1 finding from 1 review
Serious adverse events · people with sickle cell disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
All‐cause mortality · people with sickle cell disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Quality of life · people with sickle cell disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Reduction or prevention of kidney disease progression · children with sickle cell anaemia and microalbuminuria
1 finding from 1 review
Intervention not reported
Adherence to treatment (number of participants undertaking physical activity) · people with CF
It is very uncertain whether the intervention changes adherence to treatment (number of participants undertaking physical… (very low certainty).
1 finding from 1 review
Intervention not reported
Frequency of hospitalisation for respiratory infection · people with CF
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Frequency of non‐hospitalised respiratory infection · people with CF
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
FEV1 % predicted (change from baseline) · people with CF
It is very uncertain whether the intervention changes FEV1 % predicted (change from baseline) (very low certainty).
1 finding from 1 review
Intervention not reported
FVC % predicted (change from baseline) · people with CF
It is very uncertain whether the intervention changes FVC % predicted (change from baseline) (very low certainty).
1 finding from 1 review
Intervention not reported
QoL (change from baseline) · people with CF
1 finding from 1 review
Intervention not reported
Exercise capacity (change from baseline) VO2 peak · people with CF
It is very uncertain whether the intervention changes exercise capacity (change from baseline) VO2 peak (very low certainty).
1 finding from 1 review
Eradication of MRSA · adults or children with positive microbiological isolate of MRSA from a respiratory tract specimen
Active treatment showed no clear difference in eradication of MRSA: number of participants that were MRSA‐negativea compared with observation only (low certainty).
1 finding from 1 review
Quality of life: CFQ‐R respiratory domain: absolute change from baseline · adults and children with cystic fibrosis and a positive microbiological isolate of MRSA from a respiratory tract specimen
1 finding from 1 review
FEV1 % predicted: absolute change from baseline · adults and children with cystic fibrosis and a positive microbiological isolate of MRSA from a respiratory tract specimen
1 finding from 1 review
Growth · adults and children with cystic fibrosis and a positive microbiological isolate of MRSA from a respiratory tract specimen
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Exacerbation frequency · adults and children with cystic fibrosis and a positive microbiological isolate of MRSA from a respiratory tract specimen
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found