Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

573 questions · 608 findings · 115 reviews

No studies found 136 · 22.4%GRADE not reported 54 · 8.9%Very low 166 · 27.3%Low 152 · 25%Moderate 75 · 12.3%High 25 · 4.1%

Primary dental health aide (PDHA) service-delivery models (PDHA program; PDHA + intensive staffing; PDHA + robust prevention) vs Baseline pre-intervention service-delivery scenario

Projected Significant Caries (SiC) index · Alaska Native children (below age 18)

A simulation projected a 50% drop in the Significant Caries index for children (12.3 to 6.1) under the PDHA model (certainty not graded).

2 findings from 1 review

Primary dental health aide (PDHA) service-delivery models (PDHA program; PDHA + intensive staffing; PDHA + robust prevention) vs Baseline pre-intervention service-delivery scenario

Projected proportion of caries-free children (5-18 years) · Alaska Native children (below age 18)

A simulation projected 0% of children aged 5-18 would be caries-free under the baseline scenario (certainty not graded).

3 findings from 1 review

Primary dental health aide (PDHA) service-delivery models (PDHA program; PDHA + intensive staffing; PDHA + robust prevention) vs Baseline pre-intervention service-delivery scenario

Projected receipt of school-based prevention services · Alaska Native children (below age 18)

A simulation projected that over 90% of children would receive school-based prevention services under the PDHA model, up from 53% (certainty not graded).

1 finding from 1 review

Primary dental health aide (PDHA) service-delivery models (PDHA program; PDHA + intensive staffing; PDHA + robust prevention) vs Baseline pre-intervention service-delivery scenario

Projected dental care utilisation · Alaska Native children (below age 18)

A simulation projected that the PDHA program would raise dental care utilisation from 75% to 90% (certainty not graded).

1 finding from 1 review

Primary dental health aide (PDHA) service-delivery models (PDHA program; PDHA + intensive staffing; PDHA + robust prevention) vs Baseline pre-intervention service-delivery scenario

Projected mean DMFT (children below 5 years) · Alaska Native children (below age 18)

A simulation projected mean DMFT in children under 5 would fall from 7.4 to 4.9 under the PDHA model (certainty not graded).

1 finding from 1 review

Non‐integrated models of care ‐ Assertive community treatment only/Intensive case management/Specialised case management services vs usual care

Mental state Schizophrenia symptoms on C‐DIS‐R computer program for Diagnostic Interview Schedule: average score · people with both severe mental illness and substance misuse

The review found no eligible studies for this question.

1 finding from 1 review

Non‐integrated models of care ‐ Assertive community treatment only/Intensive case management/Specialised case management services vs usual care

General life satisfaction Quality of Life Interview section, scale of 1 to 7 · people with both severe mental illness and substance misuse

The review found no eligible studies for this question.

1 finding from 1 review

Non‐integrated models of care ‐ Assertive community treatment only/Intensive case management/Specialised case management services vs usual care

Lost to treatment · people with both severe mental illness and substance misuse

It is very uncertain whether non‐integrated models of care ‐ Assertive community treatment… changes leaving the study early: Lost to treatment compared with standard care (very low certainty).

1 finding from 1 review

Non‐integrated models of care ‐ Assertive community treatment only/Intensive case management/Specialised case management services vs usual care

Adverse event: Death ‐ not measured · people with both severe mental illness and substance misuse

The review found no eligible studies for this question.

1 finding from 1 review

Summary of findings table ‐ Midwife continuity models vs other models of care

Admission to neonatal special care unit or intensive care unit · childbearing women and their infants (all) (important/secondary outcomes)

Summary of findings table ‐ Midwife continuity models showed no clear difference in admission to special care nursery/neonatal intensive care unit compared with other models of care (moderate certainty).

1 finding from 1 review

Balloon (Foley or ATAD) vs vaginal prostaglandin E2

Admission to neonatal intensive care unit · third trimester induction of labour in women with a viable fetus

Balloon (Foley or ATAD) showed no clear difference in neonatal intensive care unit admission compared with vaginal prostaglandin E2 (low certainty).

1 finding from 1 review