Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

173 questions · 174 findings · 12 reviews · Headline outcomes only

No studies found 34 · 19.5%GRADE not reported 26 · 14.9%Very low 34 · 19.5%Low 40 · 23%Moderate 25 · 14.4%High 15 · 8.6%

Tetracycline vs doxycycline

Bacteriological failure · Adults and children with cholera diarrhoea

Tetracycline probably leads to lower bacteriological failure compared with doxycycline (moderate certainty).

1 finding from 1 review

Intervention not reported

Clinical outcomes: improvement in iridocyclitis at 6 months · people residing in communities endemic for onchocerciasis

It is very uncertain whether the intervention changes clinical outcomes: improvement in iridocyclitis at 6 months (very low certainty).

1 finding from 1 review

Intervention not reported

Clinical outcomes: improvement in punctate keratitis at 6 months · people residing in communities endemic for onchocerciasis

It is very uncertain whether the intervention changes clinical outcomes: improvement in punctate keratitis at 6 months (very low certainty).

1 finding from 1 review

Intervention not reported

Pain 10‐cm VAS scale (median · participants with osteoarthritis of the knee or hip
1 finding from 1 review

Intervention not reported

Function WOMAC function (range 0 to 10) (median · participants with osteoarthritis of the knee or hip
1 finding from 1 review

Intervention not reported

Minimum joint space width ( · participants with osteoarthritis of the knee or hip
1 finding from 1 review

Intervention not reported

Number of participants experiencing any adverse event ( · participants with osteoarthritis of the knee or hip

The intervention may leads to higher number of participants experiencing any adverse event ( (low certainty).

1 finding from 1 review

Intervention not reported

Number of participants withdrawn due to adverse events (median · participants with osteoarthritis of the knee or hip

The intervention may leads to higher number of participants withdrawn due to adverse events (median (low certainty).

1 finding from 1 review

Intervention not reported

Number of participants experiencing any serious adverse event (median · participants with osteoarthritis of the knee or hip

The intervention showed no clear difference in number of participants experiencing any serious adverse event (median (low certainty).

1 finding from 1 review