Diagnostic accuracy for proximal caries detection (dentin detection level) · Patients with permanent posterior teeth, proximal surfaces assessed clinically (in vivo)
Under in vivo conditions, sensor-based digital bitewing radiography had a pooled sensitivity of 0.96 (95% CI 0.91, 0.98) for proximal caries detection at the dentin detection level; ungraded.
4 findings from 1 review
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Diagnostic accuracy for proximal caries detection (dentin detection level) · Patients with permanent posterior teeth, proximal surfaces assessed clinically (in vivo)
Under in vivo conditions, visual examination had a pooled specificity of 0.76 (95% CI 0.11, 0.99) for proximal caries detection at the dentin detection level; ungraded.
4 findings from 1 review
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Diagnostic accuracy for proximal caries detection (dentin detection level) · Extracted permanent posterior teeth with proximal surfaces (in vitro)
Under in vitro conditions, visual examination had a summary ROC AUC of 0.85 for proximal caries detection at the dentin detection level; ungraded.
4 findings from 1 review
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Intervention not reported
Arrest of dentine caries
1 finding from 1 review
no estimate extracted
2 studies
GRADE not reported
Intervention not reported
Arrest of dentine caries
1 finding from 1 review
no estimate extracted
1 study
GRADE not reported
Intervention not reported
Arrest of dentine caries
1 finding from 1 review
no estimate extracted
2 studies
GRADE not reported
Discriminant power for caries severity: effect size (f) for microbial load (log10 CFU) between lesion categories · Patients with dentine carious lesions (deciduous/permanent teeth; children and adults)
The weighted effect size favoured hardness (f=2.62) over colour (f=0.46) for discriminating microbial load, supporting hardness as the more reliable examination (ungraded).
1 finding from 1 review
Discriminant power for caries severity: mean difference in log10 CFU (microbial load) between lesion categories · Patients with dentine carious lesions (deciduous/permanent teeth; children and adults)
For yellow-vs-other colour compared with soft-vs-harder hardness, hardness was significantly the more discriminant test (pooled WMD -3.87, 95% CI -4.46 to -2.87; ungraded).
6 findings from 1 review
WMD -3.867 [-4.461, -2.874]
2 studies
GRADE not reported
WMD -4.446 [-5.241, -3.650]
2 studies
GRADE not reported
WMD -0.067 [-1.877, 1.743]
2 studies
GRADE not reported
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Only one study (Beighton et al.) permitted this comparison: the mean log10 CFU difference was 2.32 for the colour contrast (black vs rest) versus 3.72 for the hardness contrast (soft vs medium/hard); hardness appeared…
1 study
GRADE not reported
WMD -4.741 [-4.979, -4.502]
2 studies
GRADE not reported
WMD -3.369 [-3.595, -3.143]
2 studies
GRADE not reported
Treatment success (caries lesion arrest or restoration survival) · Children with dentin caries lesions in the outer half of dentin on occlusal surfaces of primary teeth
Conventional restorative treatment with resin composite gave a higher treatment success rate than resin sealing for outer-half occlusal dentin caries in primary teeth (2 studies; low certainty).
1 finding from 1 review
Treatment failure (annual failure rate) · Children (aged 5-8 years) with Class-II caries in primary molars, no pulp therapy
Etching dentine for 7 s rather than 15 s lowered bulk-fill composite failure (5.8% vs 16.9% annual failure) in one RCT; low quality of evidence (ungraded).
1 finding from 1 review
Collagen-degrading bacteria · Root caries lesion biofilm
Protein-degrading bacteria capable of degrading collagen were detected in root caries biofilm.
1 finding from 1 review
no estimate extracted
1 study
GRADE not reported
Overall success (composite of clinical and radiographic success) · Vital permanent teeth (mature or immature) with deep or extremely deep caries and asymptomatic pulp or reversible pulpitis, undergoing…
At 36-month follow-up, HCSC show higher odds of clinical and radiographic success than CaOH (OR 2.34, 95% CI 1.43 to 3.84; ungraded subgroup).
3 findings from 1 review
OR 2.34 [1.43, 3.84]
2 studies · 379 participants
GRADE not reported
OR 4.44 [1.63, 12.07]
3 studies · 174 participants
GRADE not reported
OR 2.68 [1.7, 4.22]
5 studies · 552 participants
Moderate
Restoration longevity · Patients with deep caries lesions in mature or immature permanent (posterior) teeth, with no symptoms or reversible pulpitis
Cavity liners may make little or no difference to restoration longevity (high success across groups; low certainty).
1 finding from 1 review
Treatment failure · Patients with deep caries lesions in mature or immature permanent (posterior) teeth, with no symptoms or reversible pulpitis
The evidence is very uncertain about the effect of cavity liners on treatment failure; no significant difference between lined and unlined (or differently lined) restorations was found (very low certainty).
1 finding from 1 review
Postoperative hypersensitivity (POH), patient-reported (VAS score) · Patients with deep caries lesions in mature or immature permanent (posterior) teeth, with no symptoms or reversible pulpitis
The evidence is very uncertain whether cavity liners reduce postoperative hypersensitivity; no significant difference was found overall (very low certainty).
1 finding from 1 review
Tooth survival · Patients with deep caries lesions in mature or immature permanent (posterior) teeth, with no symptoms or reversible pulpitis
Cavity liners may make little or no difference to tooth survival (99.4% survival across groups; low certainty).
1 finding from 1 review
Oral health-related quality of life · Patients with deep caries lesions in mature or immature permanent (posterior) teeth, with no symptoms or reversible pulpitis
No included study reported oral health-related quality of life (a planned outcome), so no evidence is available.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Radiographic hard-tissue (dentine) barrier formation · Mature permanent (molar) teeth with deep caries and symptoms indicative of irreversible pulpitis (spontaneous pain)
Radiographic hard-tissue barrier formation did not differ significantly between partial and full pulpotomy (single RCT; ungraded).
1 finding from 1 review
Immediate bond strength (MPa) · Glass-ionomer cement bonded to caries-affected dentin (in vitro)
SDF pretreatment without a rinsing step does not affect glass-ionomer cement bond strength to caries-affected dentin (MD 0.26 MPa, 95% CI -0.30 to 0.82; ungraded).
1 finding from 1 review
Immediate bond strength (MPa) · Dental adhesives/resin composite bonded to dentin (in vitro), sound or caries-affected
Prior SDF application significantly reduces the immediate bond strength of adhesives to dentin overall (MD 7.12 MPa favoring untreated dentin, 95% CI 1.38 to 12.85; ungraded), with very high heterogeneity (I2=98%).
1 finding from 1 review