Findings

What do systematic reviews say?

182 questions · 183 findings · 20 reviews · Headline outcomes only

Sort:Best matchNewest Highest certainty Download CSV

No studies found 46 · 25.1%GRADE not reported 5 · 2.7%Very low 51 · 27.9%Low 37 · 20.2%Moderate 34 · 18.6%High 10 · 5.5%

PCC vs usual care

Length of critical care stay (hours) · cardiac surgery for the treatment of non‐surgical bleeding

1 finding from 1 review

Prothrombin complex concentrate in cardiac surgery for the treatment of coagulopathic bleeding 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 151 participants
Moderate

PCC vs usual care

Incidence of renal impairment · cardiac surgery for the treatment of non‐surgical bleeding

PCC showed no clear difference in incidence of renal impairment compared with standard treatment (low certainty).

1 finding from 1 review

Prothrombin complex concentrate in cardiac surgery for the treatment of coagulopathic bleeding 2022 · Cochrane Headline outcomes only
OR 0.72 [0.14, 3.59]
1 study · 50 participants
Low

PCC vs usual care

Bleeding (chest drain output) in mLs for the first 12 hours · cardiac surgery for the treatment of non‐surgical bleeding

1 finding from 1 review

Prothrombin complex concentrate in cardiac surgery for the treatment of coagulopathic bleeding 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 151 participants
Low

PCC vs usual care

Adverse events · cardiac surgery for the treatment of non‐surgical bleeding

The review found no eligible studies for this question.

1 finding from 1 review

Prothrombin complex concentrate in cardiac surgery for the treatment of coagulopathic bleeding 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

PCC vs FVIIa

Blood products transfused (RBC) in units ‐ intraoperative · cardiac surgery for the treatment of non‐surgical bleeding

1 finding from 1 review

Prothrombin complex concentrate in cardiac surgery for the treatment of coagulopathic bleeding 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 256 participants
Moderate

Summary of findings ‐ AZLI vs placebo

FEV1 % predicted: relative change from baseline · adults and children with CF

1 finding from 1 review

Antibiotic therapy for chronic infection with Burkholderia cepacia complex in people with cystic fibrosis 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 99 participants
Moderate

Summary of findings ‐ AZLI vs placebo

Time to next exacerbation · adults and children with CF

1 finding from 1 review

Antibiotic therapy for chronic infection with Burkholderia cepacia complex in people with cystic fibrosis 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 100 participants
Moderate

Summary of findings ‐ AZLI vs placebo

Participants hospitalised for respiratory exacerbation · adults and children with CF

Summary of findings ‐ AZLI showed no clear difference in participants hospitalised for respiratory exacerbation compared with placebo (moderate certainty).

1 finding from 1 review

Antibiotic therapy for chronic infection with Burkholderia cepacia complex in people with cystic fibrosis 2021 · Cochrane Headline outcomes only
RR 0.88 [0.53, 1.45]
1 study · 100 participants
Moderate

Summary of findings ‐ AZLI vs placebo

Adverse events (AEs) (1 or more events) · adults and children with CF

Summary of findings ‐ AZLI showed no clear difference in any AEs compared with placebo (moderate certainty).

1 finding from 1 review

Antibiotic therapy for chronic infection with Burkholderia cepacia complex in people with cystic fibrosis 2021 · Cochrane Headline outcomes only
RR 1.08 [0.98, 1.19]
1 study · 100 participants
Moderate

Summary of findings ‐ AZLI vs placebo

All‐cause mortality · adults and children with CF

Summary of findings ‐ AZLI showed no clear difference in mortality compared with placebo (moderate certainty).

1 finding from 1 review

Antibiotic therapy for chronic infection with Burkholderia cepacia complex in people with cystic fibrosis 2021 · Cochrane Headline outcomes only
RR 5.41 [0.27, 109.87]
1 study · 100 participants
Moderate

Intervention not reported

LASB vs placebo · adults with CRPS

1 finding from 1 review

Local anaesthetic sympathetic blockade for complex regional pain syndrome 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 23 participants
Moderate

Intervention not reported

Image‐guided LASB vs nonimage‐guided LASB · adults with CRPS

1 finding from 1 review

Local anaesthetic sympathetic blockade for complex regional pain syndrome 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 42 participants
Very low

Intervention not reported

LASB vs oral corticosteroids · adults with CRPS

1 finding from 1 review

Local anaesthetic sympathetic blockade for complex regional pain syndrome 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 38 participants
Very low

Intervention not reported

LASB bupivacaine + BTA vs LASB bupivacaine · adults with CRPS

1 finding from 1 review

Local anaesthetic sympathetic blockade for complex regional pain syndrome 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 9 participants
Low

Intervention not reported

Thoracic LASB + steroid vs subcutaneous local anaesthetic+ steroid · adults with CRPS

1 finding from 1 review

Local anaesthetic sympathetic blockade for complex regional pain syndrome 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 36 participants
Very low

Intervention not reported

LASB vs ultrasound block · adults with CRPS

1 finding from 1 review

Local anaesthetic sympathetic blockade for complex regional pain syndrome 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 18 participants
Low

Intervention not reported

LASB vs IVRB guanethidine · adults with CRPS

1 finding from 1 review

Local anaesthetic sympathetic blockade for complex regional pain syndrome 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 19 participants
Very low

Intervention not reported

LASB lumbar plexus vs pulsed radiofrequency lumbar plexus · adults with CRPS

1 finding from 1 review

Local anaesthetic sympathetic blockade for complex regional pain syndrome 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Very low

Intervention not reported

LASB (lidocaine + clonidine) vs IVRB (lidocaine + clonidine) · adults with CRPS

1 finding from 1 review

Local anaesthetic sympathetic blockade for complex regional pain syndrome 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 43 participants
Very low

Intervention not reported

LASB + PT+ pharmacological vs PT + pharmacological · adults with CRPS

1 finding from 1 review

Local anaesthetic sympathetic blockade for complex regional pain syndrome 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 82 participants
Very low