Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

250 questions · 253 findings · 22 reviews

No studies found 32 · 12.6%GRADE not reported 19 · 7.5%Very low 46 · 18.2%Low 83 · 32.8%Moderate 57 · 22.5%High 16 · 6.3%

Summary of findings 2: PLD alone vs other conventional chemotherapy

Overall severe adverse events (grade > 3) · recurrent platinum‐resistant EOC

It is very uncertain whether summary of findings 2: PLD alone changes overall severe adverse events (grade > 3) compared with other conventional chemotherapy (very low certainty).

1 finding from 1 review

Summary of findings 2: PLD alone vs other conventional chemotherapy

Hand‐foot syndrome (grade ≥ 3) · recurrent platinum‐resistant EOC

It is very uncertain whether summary of findings 2: PLD alone changes hand‐foot syndrome (grade ≥ 3) compared with other conventional chemotherapy (very low certainty).

1 finding from 1 review

Intervention not reported

Chemobased OS ‐ 5‐FU based chemotherapy OS · patients with resectable gastric cancer

The intervention probably leads to lower chemobased OS ‐ 5‐FU based chemotherapy OS (moderate certainty).

1 finding from 1 review

Intervention not reported

Chemobased OS ‐ Platinum‐based chemotherapy OS · patients with resectable gastric cancer

The intervention showed no clear difference in chemobased OS ‐ Platinum‐based chemotherapy OS (moderate certainty).

1 finding from 1 review

Intervention not reported

Chemobased DFS ‐ 5‐FU based chemotherapy DFS · patients with resectable gastric cancer

The intervention probably leads to lower chemobased DFS ‐ 5‐FU based chemotherapy DFS (moderate certainty).

1 finding from 1 review

Intervention not reported

Chemobased DFS ‐ Platinum‐based chemotherapy DFS · patients with resectable gastric cancer

The intervention showed no clear difference in chemobased DFS ‐ Platinum‐based chemotherapy DFS (moderate certainty).

1 finding from 1 review

Moxibustion + conventional treatment vs Western medicine

The incidence and severity of toxicities: leukopenia (WHO grade 3 to 4) · Patients with cancer receiving chemotherapy and/or radiotherapy

Moxibustion + conventional treatment showed no clear difference in the incidence and severity of toxicities: leukopenia (WHO grade 3 to… compared with conventional medicine alone (low certainty).

1 finding from 1 review

Moxibustion + conventional treatment vs Western medicine

Patient‐reported symptom: nausea/vomiting (WHO grade 3 to 4) · Patients with cancer receiving chemotherapy and/or radiotherapy

Moxibustion + conventional treatment may leads to lower patient‐reported symptom: nausea/vomiting (WHO grade 3 to 4) compared with conventional medicine alone (low certainty).

1 finding from 1 review

Moxibustion + conventional treatment vs Western medicine

Diarrhoea · Patients with cancer receiving chemotherapy and/or radiotherapy

Moxibustion + conventional treatment showed no clear difference in patient‐reported symptom: diarrhoea compared with conventional medicine alone (low certainty).

1 finding from 1 review

Moxibustion + conventional treatment vs Western medicine

Haemoglobin (g/dL) · Patients with cancer receiving chemotherapy and/or radiotherapy

Moxibustion + conventional treatment may leads to higher objective outcome measure: haemoglobin (g/L) compared with conventional medicine alone (low certainty).

1 finding from 1 review

Moxibustion + conventional treatment vs Western medicine

Objective outcome measure: platelets (× 109/L) · Patients with cancer receiving chemotherapy and/or radiotherapy

Moxibustion + conventional treatment showed no clear difference in objective outcome measure: platelet (× 109/L) compared with conventional medicine alone (low certainty).

1 finding from 1 review