Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

202 questions · 247 findings · 34 reviews

No studies found 46 · 18.6%GRADE not reported 26 · 10.5%Very low 36 · 14.6%Low 56 · 22.7%Moderate 58 · 23.5%High 25 · 10.1%

BoNT‐A vs usual care or physiotherapy

Instrumented gait analysis (kinematics) (not measured) · children with CP

The review found no eligible studies for this question.

3 findings from 1 review

BoNT‐A vs usual care or physiotherapy

Function · children with CP
3 findings from 1 review

BoNT‐A vs usual care or physiotherapy

Range of motion (passive ankle dorsiflexion) · children with CP
3 findings from 1 review

BoNT‐A vs usual care or physiotherapy

Satisfaction (not measured) · children with CP

The review found no eligible studies for this question.

2 findings from 1 review

BoNT‐A vs usual care or physiotherapy

Spasticity (ankle plantarflexors) · children with CP
3 findings from 1 review

BoNT‐A vs usual care or physiotherapy

Adverse events · children with CP

The review found no eligible studies for this question.

3 findings from 1 review

BoNT‐A vs usual care or physiotherapy

Gait assessment ‐ not measured · children with CP

The review found no eligible studies for this question.

2 findings from 1 review

BoNT‐A vs sham

Observational gait analysis (improvement) · children with CP

BoNT‐A probably leads to higher observational gait analysis (improvement) compared with placebo or sham (moderate certainty).

2 findings from 1 review

BoNT‐A vs sham

Function · children with CP
3 findings from 1 review

BoNT‐A vs sham

Range of motion (passive ankle dorsiflexion) · children with CP
3 findings from 1 review

BoNT‐A vs sham

Satisfaction · children with CP
3 findings from 1 review

BoNT‐A vs sham

Spasticity (ankle plantarflexors) · children with CP
3 findings from 1 review

BoNT‐A vs sham

Adverse events · children with CP

BoNT‐A showed no clear difference in adverse events compared with placebo or sham (moderate certainty).

3 findings from 1 review

BoNT‐A vs sham

Instrumented gait analysis (kinematics) (not measured) · children with CP

The review found no eligible studies for this question.

2 findings from 1 review

BoNT‐A vs serial casting

Instrumented gait analysis (peak ankle dorsiflexion in stance) · children with CP
3 findings from 1 review

BoNT‐A vs serial casting

Observational gait analysis · children with CP
3 findings from 1 review

BoNT‐A vs serial casting

Function · children with CP
3 findings from 1 review