Question · asked by 1 review

BoNT‐A vs sham: Observational gait analysis (improvement)

BoNT‐A probably leads to higher observational gait analysis (improvement) compared with placebo or sham (moderate certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
BoNT‐A vs placebo or sham
Observational gait analysis (improvement) · children with CP
BoNT‐A probably leads to higher observational gait analysis (improvement) compared with placebo or sham (moderate certainty).
Botulinum toxin type A in the treatment of lower limb spasticity in children with cerebral palsy (2019) · Cochrane Headline outcomes only
RR 1.66 [1.16, 2.37]4 studies · 261 participantsModerate
BoNT‐A vs placebo or sham
Observational gait analysis (improvement) · children with CP
BoNT‐A probably leads to higher observational gait analysis (improvement) compared with placebo or sham (moderate certainty).
Botulinum toxin type A in the treatment of lower limb spasticity in children with cerebral palsy (2019) · Cochrane Headline outcomes only
RR 1.9 [1.32, 2.74]3 studies · 248 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Botulinum toxin type A in the treatment of lower limb spasticity in children with cerebral palsy
2019 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.