Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

173 questions · 180 findings · 26 reviews · Headline outcomes only

No studies found 33 · 18.3%GRADE not reported 9 · 5%Very low 35 · 19.4%Low 58 · 32.2%Moderate 33 · 18.3%High 12 · 6.7%

Levofloxacin vs fluoroquinolones

Adverse effects of treatment ‐ any adverse effects · patients with chronic bacterial prostatitis

Levofloxacin showed no clear difference in adverse effects of treatment ‐ any adverse effects compared with comparator fluoroquinolone (moderate certainty).

1 finding from 1 review

Levofloxacin vs ciprofloxacin

Clinical efficacy ‐ cure or improvement at · patients with chronic bacterial prostatitis

Levofloxacin showed no clear difference in clinical efficacy ‐ cure or improvement at end of treatment compared with ciprofloxacin (low certainty).

2 findings from 1 review

Levofloxacin vs ciprofloxacin

Adverse effects of treatment ‐ any adverse effects · patients with chronic bacterial prostatitis

Levofloxacin showed no clear difference in adverse effects of treatment ‐ any adverse effects compared with ciprofloxacin (moderate certainty).

1 finding from 1 review

Lomefloxacin vs fluoroquinolones

Microbiological efficacy ‐ pathogen eradication · patients with chronic bacterial prostatitis

Lomefloxacin showed no clear difference in microbiological efficacy ‐ pathogen eradication at compared with comparator fluoroquinolone (low certainty).

1 finding from 1 review

Lomefloxacin vs fluoroquinolones

Adverse effects of treatment ‐ any adverse effects · patients with chronic bacterial prostatitis

Lomefloxacin showed no clear difference in adverse effects of treatment ‐ any adverse effects compared with comparator fluoroquinolone (moderate certainty).

1 finding from 1 review

Ciprofloxacin vs fluoroquinolones

Microbiological efficacy ‐ pathogen eradication · patients with chronic bacterial prostatitis

It is very uncertain whether ciprofloxacin changes microbiological efficacy ‐ pathogen eradication at end of treatment compared with comparator fluoroquinolone (very low certainty).

1 finding from 1 review

Antibiotics vs placebo or no treatment

Clinical treatment failure (Persistent or worsening symptoms at the end of treatment) · patients symptomatic for NTS infection

It is very uncertain whether antibiotics changes clinical treatment failure (Persistent or worsening symptoms at the… compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Antibiotics vs placebo or no treatment

Diarrhoea · patients symptomatic for NTS infection

It is very uncertain whether antibiotics changes presence of diarrhoea at 2‐4 days compared with placebo or no treatment (very low certainty).

2 findings from 1 review