Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

170 questions · 176 findings · 27 reviews · Acute Respiratory Infections

No studies found 11 · 6.3%GRADE not reported 31 · 17.6%Very low 18 · 10.2%Low 29 · 16.5%Moderate 67 · 38.1%High 20 · 11.4%

Antibiotics vs control ‐ primary outcomes

Prevention ‐ any AOM or CSOM during intervention · patients with the prevention of acute and chronic suppurative otitis media in children

Antibiotic probably leads to lower prevention ‐ any AOM or CSOM during intervention compared with control ‐ primary outcomes (moderate certainty).

1 finding from 1 review

Antibiotics vs control ‐ secondary outcomes

Side effects ‐ any clinical side effects during intervention · patients with the prevention of acute and chronic suppurative otitis media in children

Antibiotic showed no clear difference in side effects ‐ any clinical side effects during intervention compared with control ‐ secondary outcomes (moderate certainty).

1 finding from 1 review