Cochrane · systematic review · CD004401
Antibiotics for the prevention of acute and chronic suppurative otitis media in children
Leach, AJ, Morris, PS · Cochrane Database of Systematic Reviews · 2006 · Cochrane Library
Acute Respiratory InfectionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
2
current version
GRADE rated
2
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 100%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Antibiotic versus control ‐ primary outcomes for the prevention of acute and chronic suppurative otitis media in children
Population: patients with the prevention of acute and chronic suppurative otitis media in children
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Prevention ‐ any AOM or CSOM during intervention Antibiotic vs control ‐ primary outcomes | RR 0.65 [0.53, 0.79] | 14 studies · 1461 participants | Moderate Downgraded: imprecision, publication bias |
Antibiotic versus control ‐ secondary outcomes for the prevention of acute and chronic suppurative otitis media in children
Population: patients with the prevention of acute and chronic suppurative otitis media in children
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Side effects ‐ any clinical side effects during intervention Antibiotic vs control ‐ secondary outcomes | RR 1.99 [0.25, 15.89] | 12 studies · 817 participants | Moderate Downgraded: imprecision |