Findings

What do systematic reviews say?

3,584 questions · 3,695 findings · 567 reviews

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No studies found 784 · 21.2%GRADE not reported 308 · 8.3%Very low 1,036 · 28%Low 971 · 26.3%Moderate 440 · 11.9%High 156 · 4.2%

Selective serotonin reuptake inhibitors vs placebo

Treatment response · adults with trichotillomania

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacotherapy for trichotillomania 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Selective serotonin reuptake inhibitors vs placebo

Reduction of TTM symptom severityMassachusetts General Hospital Hair‐Pulling Scale (MGH‐HPS) · adults with trichotillomania

1 finding from 1 review

Pharmacotherapy for trichotillomania 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 31 participants
Very low

Selective serotonin reuptake inhibitors vs placebo

Dropouts due to adverse events · adults with trichotillomania

SSRIs showed no clear difference in tolerability of treatment ‐ dropouts due to adverse eventseDropout… compared with placebo (low certainty).

1 finding from 1 review

Pharmacotherapy for trichotillomania 2021 · Cochrane Headline outcomes only
RR 3 [0.33, 27.62]
2 studies · 78 participants
Low

TCAs with predominantly SRI actions vs placebo

Clinical Global Impressions scale change item (CGI‐I): no. of responders (long term) Post‐treatment: 1‐4 months · adults with trichotillomania

It is very uncertain whether TCAs with predominantly SRI actions changes treatment responseaClinical Global Impressions ‐ Improvement Scale… compared with placebo (very low certainty).

1 finding from 1 review

Pharmacotherapy for trichotillomania 2021 · Cochrane Headline outcomes only
RR 5.73 [0.36, 90.83]
1 study · 16 participants
Very low

TCAs with predominantly SRI actions vs placebo

Dropouts due to adverse events · adults with trichotillomania

It is very uncertain whether TCAs with predominantly SRI actions changes tolerability of treatment ‐ dropouts due to adverse eventsdDropout… compared with placebo (very low certainty).

1 finding from 1 review

Pharmacotherapy for trichotillomania 2021 · Cochrane Headline outcomes only
RR 4.45 [0.27, 73.81]
1 study · 16 participants
Very low

TCAs with predominantly SRI actions vs other TCAs

Treatment responseaPhysician‐rated Clinical Progress Scale · adults with trichotillomania

1 finding from 1 review

Pharmacotherapy for trichotillomania 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 26 participants
Low

Antioxidants vs placebo

Withdrawals due to adverse events · adults with trichotillomania

1 finding from 1 review

Pharmacotherapy for trichotillomania 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 18 participants
Low

TCAs with predominantly SRI actions vs other TCAs

Withdrawals due to adverse events · adults with trichotillomania

1 finding from 1 review

Pharmacotherapy for trichotillomania 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 26 participants
Low

Antioxidants vs placebo

Global Impressions scale change item (CGI‐I or similar): no. of responders (acute phase) · children with trichotillomania

Antioxidants showed no clear difference in treatment responseaClinical Global Impressions ‐ Improvement Scale… compared with placebo (low certainty).

1 finding from 1 review

Pharmacotherapy for trichotillomania 2021 · Cochrane Headline outcomes only
RR 2 [0.28, 14.2]
1 study · 8 participants
Low

Antioxidants vs placebo

Reduction of TTM symptom severityMassachusetts General Hospital Hair‐Pulling Scale (MGH‐HPS) · children with trichotillomania

1 finding from 1 review

Pharmacotherapy for trichotillomania 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 6 participants
Low

Antioxidants vs placebo

Withdrawals due to adverse events · children with trichotillomania

1 finding from 1 review

Pharmacotherapy for trichotillomania 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 6 participants
Low

Antipsychotics vs placebo

Global Impressions scale change item (CGI‐I or similar): no. of responders (acute phase) · adults with trichotillomania

Antipsychotics may leads to higher treatment responseaClinical Global Impressions ‐ Improvement Scale… compared with placebo (low certainty).

1 finding from 1 review

Pharmacotherapy for trichotillomania 2021 · Cochrane Headline outcomes only
RR 5.08 [1.4, 18.37]
1 study · 25 participants
Low

Antipsychotics vs placebo

Reduction of TTM symptom severityMassachusetts General Hospital Hair‐Pulling Scale (MGH‐HPS) · adults with trichotillomania

1 finding from 1 review

Pharmacotherapy for trichotillomania 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 25 participants
Low

Antipsychotics vs placebo

Withdrawals due to adverse events · adults with trichotillomania

1 finding from 1 review

Pharmacotherapy for trichotillomania 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 25 participants
Low

Compression stockings vs no treatment or placebo stockings

Change in symptoms (ranging from 1 week to 3 months) · people with varicose veins without venous ulceration

1 finding from 1 review

Graduated compression stockings for the initial treatment of varicose veins in people without venous ulceration 2021 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 232 participants
Low

Compression stockings vs compression stockings

Compliance · people with varicose veins without venous ulceration

1 finding from 1 review

Graduated compression stockings for the initial treatment of varicose veins in people without venous ulceration 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 467 participants
Low

Compression stockings vs compression stockings

Comfort, tolerance and acceptability of wearing stockings (1 week and up to 6 weeks' postpartumc) · people with varicose veins without venous ulceration

1 finding from 1 review

Graduated compression stockings for the initial treatment of varicose veins in people without venous ulceration 2021 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 578 participants
Very low

Compression stockings vs compression stockings

Quality of life · people with varicose veins without venous ulceration

The review found no eligible studies for this question.

1 finding from 1 review

Graduated compression stockings for the initial treatment of varicose veins in people without venous ulceration 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Compression stockings vs no treatment or placebo stockings

Measures of physiological function · people with varicose veins without venous ulceration

1 finding from 1 review

Graduated compression stockings for the initial treatment of varicose veins in people without venous ulceration 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 90 participants
Very low

Compression stockings vs no treatment or placebo stockings

Complications (1 week, 4 weeks and up to 6 weeks' postpartumc) · people with varicose veins without venous ulceration

1 finding from 1 review

Graduated compression stockings for the initial treatment of varicose veins in people without venous ulceration 2021 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 148 participants
Very low