What do systematic reviews say?

Subintimal angioplasty with stenting vs remote endarterectomy

Subintimal angioplasty with stenting showed no clear difference in months' limb salvage rate compared with remote endarterectomy (low certainty).

• Subintimal angioplasty for lower limb arterial chronic total occlusions 2016 · Cochrane Headline outcomes only
  RR 0.97 [0.9, 1.05]
  1 study · 95 participants
  Low

Subintimal angioplasty with stenting vs remote endarterectomy

Subintimal angioplasty with stenting showed no clear difference in complications compared with remote endarterectomy (low certainty).

• Subintimal angioplasty for lower limb arterial chronic total occlusions 2016 · Cochrane Headline outcomes only
  RR 0.77 [0.14, 4.42]
  1 study · 95 participants
  Low

OUTBACK re‐entry catheter vs manual re‐entry

• Subintimal angioplasty for lower limb arterial chronic total occlusions 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 52 participants
  GRADE not reported

Intervention not reported

• Blood pressure‐lowering efficacy of loop diuretics for primary hypertension 2015 · Cochrane Headline outcomes only
  no estimate extracted
  9 studies · 460 participants
  Low

Intervention not reported

• Blood pressure‐lowering efficacy of loop diuretics for primary hypertension 2015 · Cochrane Headline outcomes only
  no estimate extracted
  9 studies · 460 participants
  Low

Intervention not reported

• Blood pressure lowering efficacy of dual alpha and beta blockers for primary hypertension 2015 · Cochrane Headline outcomes only
  no estimate extracted
  8 studies · 1007 participants
  Low

Intervention not reported

• Blood pressure lowering efficacy of dual alpha and beta blockers for primary hypertension 2015 · Cochrane Headline outcomes only
  no estimate extracted
  8 studies · 1007 participants
  Low

Intervention not reported

• Blood pressure lowering efficacy of dual alpha and beta blockers for primary hypertension 2015 · Cochrane Headline outcomes only
  no estimate extracted
  7 studies · 977 participants
  Low

Intervention not reported

• Blood pressure lowering efficacy of dual alpha and beta blockers for primary hypertension 2015 · Cochrane Headline outcomes only
  no estimate extracted
  8 studies · 1007 participants
  Very low

Intervention not reported

• Blood pressure lowering efficacy of dual alpha and beta blockers for primary hypertension 2015 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 1412 participants
  Moderate

Intervention not reported

• Atorvastatin for lowering lipids 2015 · Cochrane Headline outcomes only
  no estimate extracted
  188 studies · 21941 participants
  High

Intervention not reported

• Atorvastatin for lowering lipids 2015 · Cochrane Headline outcomes only
  no estimate extracted
  80 studies · 9310 participants
  High

Intervention not reported

• Atorvastatin for lowering lipids 2015 · Cochrane Headline outcomes only
  no estimate extracted
  37 studies · 3296 participants
  High

Intervention not reported

• Atorvastatin for lowering lipids 2015 · Cochrane Headline outcomes only
  no estimate extracted
  37 studies · 4281 participants
  High

Intervention not reported

• Atorvastatin for lowering lipids 2015 · Cochrane Headline outcomes only
  no estimate extracted
  34 studies · 3688 participants
  Very low

Intervention not reported

The intervention showed no clear difference in incidence of pulmonary tuberculosis in children with HIV infection ‐… (moderate certainty).

• Antibiotics for preventing lower respiratory tract infections in high‐risk children aged 12 years and under 2015 · Cochrane Headline outcomes only
  RR 0.64 [0.32, 1.29]
  2 studies · 810 participants
  Moderate

Intervention not reported

• Antibiotics for preventing lower respiratory tract infections in high‐risk children aged 12 years and under 2015 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 312 participants
  Moderate

Intervention not reported

• Antibiotics for preventing lower respiratory tract infections in high‐risk children aged 12 years and under 2015 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 106 participants
  Moderate

Intervention not reported

The intervention leads to lower episodes of pulmonary exacerbations ‐ azithromycin prophylaxis only (high certainty).

• Antibiotics for preventing lower respiratory tract infections in high‐risk children aged 12 years and under 2015 · Cochrane Headline outcomes only
  RR 0.6 [0.48, 0.76]
  2 studies · 323 participants
  High

Intervention not reported

The intervention probably leads to lower incidence of Pneumocystis carinii pneumonia infection in children… (moderate certainty).

• Antibiotics for preventing lower respiratory tract infections in high‐risk children aged 12 years and under 2015 · Cochrane Headline outcomes only
  RR 0.03 [0, 0.47]
  1 study · 160 participants
  Moderate