Findings

What do systematic reviews say?

4,315 questions · 23,557 findings · 2,311 reviews

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No studies found 4,183 · 17.8%GRADE not reported 3,930 · 16.7%Very low 5,371 · 22.8%Low 5,787 · 24.6%Moderate 3,320 · 14.1%High 966 · 4.1%

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Brief admission to psychiatric hospital by self‐referral plus treatment as usual vs treatment

Suicidality: mean number of suicide attempts over the preceding 2 weeks Timing of outcome assessment: 12 months · adults meeting 3 or more diagnostic criteria for borderline personality disorder

1 finding from 1 review

Crisis interventions for adults with borderline personality disorder 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 125 participants
Very low

Intervention not reported

Symblepharon Presence of symblepharon · people with severe acute ocular burns

The intervention showed no clear difference in symblepharon Presence of symblepharon (low certainty).

1 finding from 1 review

Amniotic membrane transplantation for acute ocular burns 2022 · Cochrane Headline outcomes only
RR 0.89 [0.56, 1.42]
2 studies · 92 participants
Low

Intervention not reported

Symblepharon Presence of symblepharon · people with moderate acute ocular burns

It is very uncertain whether the intervention changes symblepharon Presence of symblepharon (very low certainty).

1 finding from 1 review

Amniotic membrane transplantation for acute ocular burns 2022 · Cochrane Headline outcomes only
RR 0.41 [0.02, 9.48]
1 study · 36 participants
Very low

Malaria rapid diagnostic test (mRDT) vs clinical diagnosis

Antimalarial prescribing to microscopy‐ or PCR‐negative people · people with suspected malaria

Malaria rapid diagnostic test (mRDT) probably leads to lower antimalarial prescribing to microscopy‐ or PCR‐negative people compared with clinical diagnosis (moderate certainty).

1 finding from 1 review

Adding rapid diagnostic tests to community‐based programmes for treating malaria 2022 · Cochrane Headline outcomes only
RR 0.17 [0.07, 0.4]
7877 participants
Moderate

Malaria rapid diagnostic test (mRDT) vs clinical diagnosis

Antibiotic prescribing to microscopy‐ or PCR‐negative people · people with suspected malaria

Malaria rapid diagnostic test (mRDT) probably leads to higher antibiotic prescribing to microscopy‐ or PCR‐negative people compared with clinical diagnosis (moderate certainty).

1 finding from 1 review

Adding rapid diagnostic tests to community‐based programmes for treating malaria 2022 · Cochrane Headline outcomes only
RR 2.02 [1.21, 3.37]
5179 participants
Moderate

Oral plus nebulised antibiotics vs oral antibiotics plus nebulised placebo

FEV1 % predicted: absolute change from baseline · adults and children with cystic fibrosis and a positive microbiological isolate of MRSA from a respiratory tract specimen

1 finding from 1 review

Interventions for the eradication of meticillin‐resistant Staphylococcus aureus (MRSA) in people with cystic fibrosis 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 25 participants
Low

Active treatment vs observation

FEV1 % predicted: absolute change from baseline · adults or children with positive microbiological isolate of MRSA from a respiratory tract specimen

1 finding from 1 review

Interventions for the eradication of meticillin‐resistant Staphylococcus aureus (MRSA) in people with cystic fibrosis 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 58 participants
Very low

Letrozole vs laparoscopic ovarian drilling

Multiple pregnancy rate · infertile women with polycystic ovary syndrome

It is very uncertain whether letrozole changes multiple pregnancy rate compared with laparoscopic ovarian drilling (very low certainty).

1 finding from 1 review

Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome 2022 · Cochrane Headline outcomes only
OR 3 [0.12, 74.9]
1 study · 141 participants
Very low

Letrozole with or without adjuncts vs SERMs with or without adjuncts followed by timed intercourse

Clinical pregnancy rate · infertile women with polycystic ovary syndrome

Letrozole with or without adjuncts leads to higher clinical pregnancy rate compared with SERMs with or without adjuncts followed by timed intercourse (high certainty).

1 finding from 1 review

Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome 2022 · Cochrane Headline outcomes only
OR 1.69 [1.45, 1.98]
23 studies · 3321 participants
High

Letrozole with or without adjuncts vs SERMs with or without adjuncts followed by timed intercourse

Miscarriage · infertile women with polycystic ovary syndrome

Letrozole with or without adjuncts showed no clear difference in miscarriage rate per pregnancy compared with SERMs with or without adjuncts followed by timed intercourse (high certainty).

1 finding from 1 review

Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome 2022 · Cochrane Headline outcomes only
OR 0.94 [0.66, 1.32]
15 studies · 736 participants
High

Letrozole with or without adjuncts vs SERMs with or without adjuncts followed by timed intercourse

Multiple pregnancy rate · infertile women with polycystic ovary syndrome

Letrozole with or without adjuncts showed no clear difference in multiple pregnancy rate compared with SERMs with or without adjuncts followed by timed intercourse (high certainty).

1 finding from 1 review

Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome 2022 · Cochrane Headline outcomes only
OR 0.74 [0.42, 1.32]
14 studies · 2247 participants
High

Letrozole vs laparoscopic ovarian drilling

Clinical pregnancy rate · infertile women with polycystic ovary syndrome

Letrozole showed no clear difference in clinical pregnancy rate compared with laparoscopic ovarian drilling (low certainty).

1 finding from 1 review

Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome 2022 · Cochrane Headline outcomes only
OR 1.47 [0.95, 2.28]
3 studies · 376 participants
Low

Letrozole vs laparoscopic ovarian drilling

Miscarriage · infertile women with polycystic ovary syndrome

Letrozole showed no clear difference in miscarriage rate per pregnancy compared with laparoscopic ovarian drilling (low certainty).

1 finding from 1 review

Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome 2022 · Cochrane Headline outcomes only
OR 0.65 [0.22, 1.92]
3 studies · 122 participants
Low

Yoga vs no exercise

Depression · patients with non‐specific chronic low back pain

1 finding from 1 review

Yoga for chronic non‐specific low back pain 2022 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 241 participants
Low