Cochrane · systematic review · CD009379
Amniotic membrane transplantation for acute ocular burns
Clare, G, Bunce, C, Tuft, S · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
12
current version
GRADE rated
12
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 4 · 33.3%Low 8 · 66.7%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Show all 2 versionsAmniotic membrane transplant (AMT) for moderate ocular burns
Population: people with moderate acute ocular burns
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Failure of re‐epithelialisation by day 21 post‐injury Image analysis of digital photographs | RR 0.18 [0.02, 1.31] | 1 study · 36 participants | Very low Downgraded: risk of bias |
**Visual acuity at final | no estimate extracted | 1 study · 36 participants | Low Downgraded: risk of bias |
Corneal neovascularisation Number of quadrants affected | RR 0.56 [0.21, 1.48] | 1 study · 36 participants | Very low Downgraded: risk of bias |
Symblepharon Presence of symblepharon | RR 0.41 [0.02, 9.48] | 1 study · 36 participants | Very low Downgraded: risk of bias |
Time‐to‐epithelialisation (days) | no estimate extracted | 1 study · 36 participants | Very low Downgraded: risk of bias |
Adverse effects | no estimate extracted | 1 study · 36 participants | Low Downgraded: risk of bias |
Amniotic membrane transplant (AMT) for severe ocular burns
Population: people with severe acute ocular burns
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Failure of re‐epithelialisation by day 21 post‐injury Image analysis of digital photographs | RR 1.03 [0.94, 1.12] | 2 studies · 92 participants | Low Downgraded: risk of bias |
**Visual acuity at final | no estimate extracted | 2 studies · 92 participants | Low Downgraded: risk of bias |
Corneal neovascularisation Number of quadrants or central cornea involved | RR 0.84 [0.66, 1.06] | 2 studies · 92 participants | Low Downgraded: risk of bias |
Symblepharon Presence of symblepharon | RR 0.89 [0.56, 1.42] | 2 studies · 92 participants | Low Downgraded: risk of bias |
Time‐to‐epithelialisation (days) | no estimate extracted | 2 studies · 92 participants | Low Downgraded: risk of bias |
Adverse effects | no estimate extracted | 2 studies · 92 participants | Low Downgraded: risk of bias |