Change in abutment tooth mobility at 60 months · Partially edentulous patients treated with a removable dental prosthesis (RDP)
RDP with I-bar clasps / mesial rests showed no clear difference in change in abutment tooth mobility at 60 months compared with RDP with circumferential clasps / distal rests; GRADE not reported.
1 finding from 1 review
Presence of TMJ sounds · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Intra-articular injection of sodium hyaluronate led to lower presence of TMJ sounds compared with intra-articular injection of corticosteroids (betamethasone); GRADE not reported.
1 finding from 1 review
Extraoral masticatory muscle tenderness (number of tender sites), change from baseline · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Glucosamine sulfate (oral) showed no clear difference in extraoral masticatory muscle tenderness (number of tender sites),… compared with ibuprofen (oral); GRADE not reported.
1 finding from 1 review
Participant global self-assessment · People with erosive oral lichen planus
1 finding from 1 review
One study (Passeron 2007) assessed participant global self-assessment on a 5-point scale: 5/6 participants in the 1% pimecrolimus group rated their improvement as moderate or important versus 1/6 in the placebo group…
1 study · 12 participants
GRADE not reported
Laser therapy
Outcome not reported · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
The review found no eligible studies for this question.
1 finding from 1 review
Complications (adverse effects) · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Diclofenac sodium (oral NSAID) showed no clear difference in complications (adverse effects) compared with occlusal splint therapy; GRADE not reported.
1 finding from 1 review
Change in probing pocket depth (PPD) · People with at least one dental implant affected by perimplantitis
Nanocrystalline hydroxyapatite (Ostim) led to lower change in probing pocket depth (PPD) compared with bovine-derived xenograft (Bio-Oss) plus resorbable barrier; GRADE not reported.
1 finding from 1 review
Eating a normally varied diet · People of any age with erosive lichen planus affecting the oral, anogenital, and/or oesophageal regions
The review found no eligible studies for this question.
1 finding from 1 review
Framework survival (5 years) · Patients with implant-supported FDPs; split-mouth, 5-year
1 finding from 1 review
95% (20/21) titanium and 100% cast gold frameworks surviving 5 years; could not calculate an estimate of relative risk from the data as presented; non-significant differences in maintenance visits and alveolar bone loss
1 study · 21 participants
GRADE not reported
Reported pain (mm on VAS), change from baseline · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Glucosamine sulfate (oral) showed no clear difference in reported pain (mm on VAS), change from baseline compared with ibuprofen (oral); GRADE not reported.
1 finding from 1 review
Patient satisfaction · Partially edentulous patients treated with a distal-extension RDP
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Glucosamine sulfate (oral) showed no clear difference in brief Pain Inventory (BPI) - pain intensity, change from baseline compared with ibuprofen (oral); GRADE not reported.
1 finding from 1 review
Complications and side effects · People with at least one dental implant affected by perimplantitis
1 finding from 1 review
Change in probing pocket depth (PPD) · People with at least one dental implant affected by perimplantitis
Metronidazole gel 25% (local antibiotic) showed no clear difference in change in probing pocket depth compared with ultrasonic debridement; GRADE not reported.
1 finding from 1 review
Post-operative hypersensitivity, tooth vitality, prosthesis retention and secondary caries · Patients receiving cemented FDPs; split-mouth
1 finding from 1 review
No difference in post-operative hypersensitivity, tooth vitality, prosthesis retention, and secondary caries; paired data not provided in the correct form; trial at high risk of bias (narrative)
1 study
GRADE not reported
Pain reduction (VAS 0-100) · People with erosive oral lichen planus
1 finding from 1 review
In the Hegarty 2002 cross-over trial (n=22), no statistical testing of the pain score (VAS 0 to 100) was reported; it is not clear whether the difference is statistically significant (fluticasone mean score 19.8 versus…
1 study · 22 participants
GRADE not reported
Implant failure · People with at least one dental implant affected by perimplantitis
1 finding from 1 review
Prosthesis survival and crestal bone loss (5 years) · Patients with tooth/implant-supported FDPs; split-mouth
1 finding from 1 review
5-year prosthesis survival · Patients with a shortened dental arch (missing posterior teeth)
Fixed dental prosthesis (cantilever FDP) showed no clear difference in prosthesis survival compared with removable dental prosthesis (RDP); GRADE not reported.
1 finding from 1 review
Physician Global Assessment (clinical signs, complete response) · People with erosive oral lichen planus
Fluocinonide in adhesive base showed no clear difference in physician Global Assessment (clinical signs, complete response) compared with placebo; GRADE not reported.
1 finding from 1 review