Question · asked by 1 review

Glucosamine sulfate (oral) vs ibuprofen: Reported pain (mm on VAS), change from baseline

Population
Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria
Intervention
Glucosamine sulfate (oral)
Comparison
ibuprofen
Outcome
Reported pain (mm on VAS), change from baseline

Glucosamine sulfate (oral) showed no clear difference in reported pain (mm on VAS), change from baseline compared with ibuprofen (oral); GRADE not reported.

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Glucosamine sulfate (oral) vs Ibuprofen (oral)
Reported pain (mm on VAS), change from baseline · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria · 90 days
Glucosamine sulfate (oral) showed no clear difference in reported pain (mm on VAS), change from baseline compared with ibuprofen (oral); GRADE not reported.
Interventions for managing temporomandibular joint osteoarthritis (2012) · Cochrane All outcomes
MD -4.57 [-9.91, 0.77]1 study · 45 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for managing temporomandibular joint osteoarthritis
2012 · Cochrane All outcomes
2011-09Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.