Question · asked by 1 review

Metronidazole gel 25% (local antibiotic) vs Ultrasonic debridement: Change in probing pocket depth (PPD)

Population
People with at least one dental implant affected by perimplantitis
Intervention
Metronidazole gel 25% (local antibiotic)
Comparison
Ultrasonic debridement
Outcome
Change in probing pocket depth (PPD)

Metronidazole gel 25% (local antibiotic) showed no clear difference in change in probing pocket depth compared with ultrasonic debridement; GRADE not reported.

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Metronidazole gel 25% (local antibiotic) vs Ultrasonic debridement
Change in probing pocket depth · People with at least one dental implant affected by peri-implantitis · 12 weeks
Metronidazole gel 25% (local antibiotic) showed no clear difference in change in probing pocket depth compared with ultrasonic debridement; GRADE not reported.
Interventions for replacing missing teeth: treatment of peri‐implantitis (2012) · Cochrane All outcomes
After 12 weeks there was no statistically significant difference in PPD changes.1 study · 27 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for replacing missing teeth: treatment of peri‐implantitis
2012 · Cochrane All outcomes
2011-06Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.