Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,413 questions · 2,602 findings · 93 reviews · Oral Health

No studies found 452 · 17.4%GRADE not reported 1,582 · 60.8%Very low 392 · 15.1%Low 122 · 4.7%Moderate 53 · 2%High 1 · 0%

Clofazimine (100 mg daily for 30 days, then 100 mg every other day) vs placebo

Adverse effects · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review

LongoVital (herbal component alone) vs placebo

Number of days of ulcers (monthly average) · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…

LongoVital (herbal component alone) showed no clear difference in number of days of ulcers (monthly average) compared with placebo; GRADE not reported.

1 finding from 1 review

Erbium:YAG laser vs Air-abrasive device (Perio-Flow)

Marginal bone level change · People with at least one dental implant affected by perimplantitis

Er:YAG laser showed no clear difference in radiographic marginal bone level change compared with air-abrasive device (Perio-Flow); GRADE not reported.

1 finding from 1 review

Iontophoretically applied corticosteroids

Outcome not reported · Adults (>18 years) with temporomandibular joint osteoarthritis (TMJ OA) diagnosed by RDC/TMD or compatible criteria

The review found no eligible studies for this question.

1 finding from 1 review

Crestal incision vs Vestibular incision

Biological complications · People with dental implants

Crestal incision led to lower biological complications compared with vestibular incision; GRADE not reported.

1 finding from 1 review

Technique to increase peri-implant keratinised/attached mucosa vs No increase of keratinised/attached mucosa

Outcome not reported · Patients receiving dental implants

The review found no eligible studies for this question.

1 finding from 1 review

Subantimicrobial dose doxycycline (20 mg twice daily for 90 days) vs placebo

Average number of new lesions per week · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…

Subantimicrobial dose doxycycline (20 mg twice daily for 90 days) led to lower number of new lesions per day compared with placebo; GRADE not reported.

1 finding from 1 review

Tetracycline suspension (250 mg, held in mouth 2 minutes then swallowed, four times daily for 5 days) vs placebo

Adjusted maximum ulcer size and adjusted maximum pain · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review

LongoVital (herbal component alone) vs placebo

Number of ulcer-free days and number of new ulcers · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review
  • Kolseth 2005 (high risk of bias): 40 patients randomised to the herbal component of LongoVital alone or placebo; data presented as medians with 95% CIs, unsuitable for further analysis; no statistically significant…
    1 study · 40 participants
    GRADE not reported

Tooth/implant FDP with rigid connectors vs Tooth/implant FDP with non-rigid connectors

Non-scheduled maintenance visits · Patients with tooth/implant-supported FDPs; split-mouth
1 finding from 1 review

Vitamin B12 (sublingual, 1000 mcg daily for 6 months) vs placebo

Frequency of outbreaks per month · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…

Vitamin B12 (sublingual, 1000 mcg daily for 6 months) led to lower frequency of outbreaks per month compared with placebo; GRADE not reported.

1 finding from 1 review

One suturing technique/material vs A different suturing technique/material

Outcome not reported · Patients receiving dental implants

The review found no eligible studies for this question.

1 finding from 1 review