Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,018 questions · 3,100 findings · 369 reviews · Headline outcomes only

No studies found 774 · 25%GRADE not reported 108 · 3.5%Very low 727 · 23.5%Low 840 · 27.1%Moderate 474 · 15.3%High 177 · 5.7%

Percutaneous ethanol injection vs radiofrequency ablation

Mortality at maximal · people with early‐ or very early‐stage hepatocellular carcinoma ineligible for surgery

It is very uncertain whether percutaneous alcohol injection changes mortality at maximal compared with radiofrequency ablation (very low certainty).

1 finding from 1 review

Percutaneous ethanol injection vs radiofrequency ablation

Cancer‐related mortality at maximal · people with early‐ or very early‐stage hepatocellular carcinoma ineligible for surgery

Percutaneous alcohol injection may leads to higher cancer‐related mortality at maximal compared with radiofrequency ablation (low certainty).

1 finding from 1 review

Percutaneous ethanol injection vs radiofrequency ablation

Serious adverse events (number of participants) · people with early‐ or very early‐stage hepatocellular carcinoma ineligible for surgery

It is very uncertain whether percutaneous alcohol injection changes serious adverse events (number of participants) compared with radiofrequency ablation (very low certainty).

1 finding from 1 review

Percutaneous ethanol injection vs radiofrequency ablation

Serious adverse events (number of events) · people with early‐ or very early‐stage hepatocellular carcinoma ineligible for surgery

It is very uncertain whether percutaneous alcohol injection changes serious adverse events (number of events) compared with radiofrequency ablation (very low certainty).

1 finding from 1 review

Targeted mass media intervention vs targeted mass media intervention plus personalised content

Intake meeting target from dietary guidelines, 3 months from baseline · adult, ethnic minority groups: Latino immigrants, elderly Chinese immigrants, self‐described Americans of African heritage

It is very uncertain whether targeted mass media intervention changes intake meeting target from dietary guidelines, 3 months from baseline compared with targeted mass media intervention plus personalised content (very low certainty).

1 finding from 1 review

Targeted mass media intervention vs targeted mass media intervention plus personalised content

Changes in dietary composition, 12 months from baseline · adult, ethnic minority groups: Latino immigrants, elderly Chinese immigrants, self‐described Americans of African heritage
1 finding from 1 review

Targeted mass media intervention vs targeted mass media intervention plus personalised content

Weekly physical activity meeting target from guidelines, 3 months from baseline · adult, ethnic minority groups: Latino immigrants, elderly Chinese immigrants, self‐described Americans of African heritage

It is very uncertain whether targeted mass media intervention changes weekly physical activity meeting target from guidelines, 3 months… compared with targeted mass media intervention plus personalised content (very low certainty).

1 finding from 1 review