Disease-free survival · Adults with oral cavity cancer (tongue or floor of mouth) and clinically negative neck nodes
1 finding from 1 review
Disease-free survival: Pandey 2018 reported 83% (superselective) vs 91% (selective) at median 36 months, not significant (P=0.69); unable to analyse (variable follow-up); 32 participants (1 RCT).
1 study · 32 participants
Very low
Patient-reported need for analgesics · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment
The review found no eligible studies for this question.
1 finding from 1 review
Improvement in occlusion (Peer Assessment Rating (PAR) or other validated scale) · Adolescents and adults with malocclusion undergoing orthodontic treatment with fixed or removable appliances
1 finding from 1 review
Woodhouse 2015 (81 participants, 22 dropouts): PAR reduction intervention median 28.0 (IQR 21.0-38.0), control median 29.0 (IQR 24.0-31.0), placebo median 27.0 (IQR 20.0-35.0); percentage improvement medians 88.9 /…
1 study · 59 participants
GRADE not reported
Patient-reported need for analgesics · Adolescents and adults with malocclusion undergoing orthodontic treatment with fixed or removable appliances
Light vibrational forces (LVF) showed no clear difference in patient-reported need for analgesics during first week of initial… compared with conventional orthodontic appliance treatment (placebo or no adjunct) (low certainty).
1 finding from 1 review
Orthodontic tooth movement (OTM) during alignment stage · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment
It is very uncertain whether low level laser therapy (LLLT) changes rate of orthodontic tooth movement during alignment stage… compared with conventional orthodontic appliance treatment (very low certainty).
1 finding from 1 review
Adverse events associated with treatment · Adults with oral cavity or oropharyngeal cancer
1 finding from 1 review
Total mortality · Adults with oral cavity or oropharyngeal cancer with nodal disease (stage N2 or N3)
PET-CT following chemoradiotherapy (neck dissection only if… showed no clear difference in total mortality compared with planned neck dissection before or after chemoradiotherapy (moderate certainty).
1 finding from 1 review
Adverse events associated with treatment · Adults with oral cavity cancer
1 finding from 1 review
Adverse events (BHNCSG 1998): flap necrosis, wound infection, fistula, vascular rupture, haematoma, seroma, chyle fistula; no complications in 45/76 modified radical ND and 54/72 supraomohyoid ND; 2 vs 1 postoperative…
1 study · 148 participants
Low
Rate of maxillary molar intrusion for correction of anterior open bite · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment
1 finding from 1 review
Two studies (62 participants), not pooled. Abellan 2021: no significant difference in molar intrusion at 3 months (1.25 vs 1.72 mm) or 6 months (1.09 vs 1.28 mm), nor rate per month. Hasan 2022: increased intrusion…
2 studies · 62 participants
GRADE not reported
Oral health-related quality of life · Adolescents and adults with malocclusion undergoing orthodontic treatment with fixed or removable appliances
1 finding from 1 review
Adverse events associated with treatment · Adults with oral cavity or oropharyngeal cancer
The review found no eligible studies for this question.
1 finding from 1 review
Mean change in BCVA at 1 month (logMAR) · people with acute non‐arteritic CRAO
1 finding from 1 review
Quality of life measures at 1 month · people with acute non‐arteritic CRAO
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events at 1 month · people with acute non‐arteritic CRAO
1 finding from 1 review
Disease control (healing of skin lesions) at day 21 · bullous pemphigoid
Clobetasol propionate cream probably leads to higher disease control (healing of skin lesions) at day 21 compared with oral prednisone (moderate certainty).
1 finding from 1 review
Treatment‐related mortality at 1 year (mITT) · bullous pemphigoid
Doxycycline probably leads to lower treatment‐related mortality at 1 year (mITT) compared with prednisolone (moderate certainty).
1 finding from 1 review
Quality of life (DLQI) adjusted for baseline DLQI, disease severity, age, Karnovsky score, baseline versus week 52. A lower score is more favourable. · bullous pemphigoid
1 finding from 1 review
Number of participants with grade 3‐4 (severe or life‐threatening) treatment‐related adverse events at 1 year (raw data) · bullous pemphigoid
Doxycycline probably leads to lower number of participants with grade 3‐4 (severe or life‐threatening)… compared with prednisolone (moderate certainty).
1 finding from 1 review
Disease control · bullous pemphigoid
It is very uncertain whether prednisone plus azathioprine changes disease control (at 6 months) compared with prednisone (very low certainty).
1 finding from 1 review
Mortality (at 6 months) · bullous pemphigoid
It is very uncertain whether prednisone plus azathioprine changes mortality (at 6 months) compared with prednisone (very low certainty).
1 finding from 1 review