Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,556 questions · 2,794 findings · 119 reviews · All outcomes

No studies found 489 · 17.5%GRADE not reported 1,719 · 61.5%Very low 399 · 14.3%Low 128 · 4.6%Moderate 58 · 2.1%High 1 · 0%

Root canal medicaments vs No medicaments, placebo, or a different type of medicament

Outcome not reported · Patients (mainly children and young adults) with a history of dental trauma and a diagnosis of luxation (intrusion, extrusion, or lateral…

The review found no eligible studies for this question.

1 finding from 1 review

Acupuncture vs sham

Adverse events · Adults with dry mouth due to radiotherapy (head and neck cancer) or Sjogren's Syndrome
1 finding from 1 review

Immediate mobilization vs 2 weeks delayed mobilization (IMF)

Post-operative adverse events and complications · Adults with mandibular fractures excluding condyles (fixed with 2 mm titanium miniplates)
1 finding from 1 review
  • One wound separation and one infection in the immediate-mobilization group. Inferior alveolar nerve status (scale 1 to 3) showed no significant difference at 6 weeks (P=0.76), 3 months (P=0.87) or 6 months (P=0.99).…
    1 study
    GRADE not reported

Hyperbaric oxygen vs No HBO therapy

Cost‐effectiveness · Patients who have had radiotherapy and who have missing teeth that require replacement with osseointegrated dental implants

The review found no eligible studies for this question.

1 finding from 1 review

Hyperbaric oxygen vs No HBO therapy

Implant failure · Patients who have had radiotherapy and who have missing teeth that require replacement with osseointegrated dental implants

Hyperbaric oxygen (HBO) therapy showed no clear difference in implant failure compared with no HBO therapy; GRADE not reported.

1 finding from 1 review

Hyperbaric oxygen vs No HBO therapy

Postimplantation complications · Patients who have had radiotherapy and who have missing teeth that require replacement with osseointegrated dental implants

Hyperbaric oxygen (HBO) therapy showed no clear difference in postimplantation complications compared with no HBO therapy; GRADE not reported.

1 finding from 1 review

Locking plate vs 2 mm non-locking titanium plates

Restoration of function (functional occlusion; bite force as surrogate) · Adults (16 to 68 years) with mandibular fractures excluding condylar involvement
1 finding from 1 review
  • Functional occlusion was achieved in all participants in both intervention groups (Agarwal 2011); the measurement of this outcome was not clearly reported. Bite force was reported as a surrogate/proxy outcome.
    1 study
    GRADE not reported

Prophylactic systemic antibiotics (amoxicillin) vs placebo or no antibiotic

Implant failure · Adults undergoing dental implant placement

Prophylactic systemic antibiotics (amoxicillin) probably leads to lower implant failure compared with no antibiotics or placebo (moderate certainty).

1 finding from 1 review

One microplate plus one miniplate vs Two miniplates

Efficacy and stability of fixation (bite force) · Adults with isolated mandibular fractures in the interforaminal region
1 finding from 1 review
  • Only one study (Gupta 2012) compared one microplate in conjunction with one miniplate versus two miniplates in isolated interforaminal fractures; however, the data reported in the trial did not satisfy the review's…
    1 study
    GRADE not reported

Fixation (splinting) vs No splint, or a different type or duration of splint

Outcome not reported · Patients (mainly children and young adults) with a history of dental trauma and a diagnosis of luxation (intrusion, extrusion, or lateral…

The review found no eligible studies for this question.

1 finding from 1 review

Prophylactic systemic antibiotics (amoxicillin) vs placebo or no antibiotic

Adverse events · Adults undergoing dental implant placement

Prophylactic systemic antibiotics (amoxicillin) showed no clear difference in adverse events compared with no antibiotics or placebo; GRADE not reported.

1 finding from 1 review