Intervention not reported
Seizure freedom 1 study reported the incidence of seizure frequency in the intervention and placebo group The results show a trend in favour of the AED group · people with epilepsy and intellectual disability
The intervention showed no clear difference in seizure freedom 1 study reported the incidence of seizure frequency… (low certainty).
1 finding from 1 review
Intervention not reported
Responder rate (≥ 50% reduction in overall seizure frequency) · people with epilepsy and intellectual disability
The intervention may leads to higher responder rate (≥ 50% reduction in overall seizure frequency) (low certainty).
1 finding from 1 review
Intervention not reported
Responder rate (≥ 50% reduction in rate of drop seizures) · people with epilepsy and intellectual disability
The intervention showed no clear difference in responder rate (≥ 50% reduction in rate of drop seizures) (low certainty).
1 finding from 1 review
Intervention not reported
Adverse events 4 studies reported the frequency of self reported adverse events in the AED and placebo groups The results show a trend in favour of the placebo groups · people with epilepsy and intellectual disability
The intervention showed no clear difference in adverse events 4 studies reported the frequency of self reported… (moderate certainty).
1 finding from 1 review
Intervention not reported
Although a higher percentage of people in the ATL and aCCT groups fell within Class I (seizure free) and Class II (> 50% reduction in seizures), no significant differences in seizure frequency were noted between the groups at 2 years after surgery... · people with temporal lobe epilepsy and intellectual disabilities
1 finding from 1 review
Intervention not reported
Co‐operation during induction ‐ Video 'fairytale' vs. no audiovisual aid (Passive) ICC = 0 (perfect vs. poor‐moderate compliance) · children
It is very uncertain whether the intervention changes co‐operation during induction ‐ Video 'fairytale' vs. no audiovisual… (very low certainty).
1 finding from 1 review
Intervention not reported
Co‐operation during induction ‐ 2 parents vs. 1 parent Poor compliance: ICC > 6 · children
It is very uncertain whether the intervention changes co‐operation during induction ‐ 2 parents vs. 1 parent Poor… (very low certainty).
1 finding from 1 review
Intervention not reported
Anxiety during induction ‐ Parental presence vs. midazolam mYPAS. Scale from: 1 to 100. · children
1 finding from 1 review
Intervention not reported
Co‐operation during induction ‐ Parental presence vs. midazolam Poor compliance: ICC > 6 · children
It is very uncertain whether the intervention changes co‐operation during induction ‐ Parental presence vs. midazolam Poor… (very low certainty).
1 finding from 1 review
Intervention not reported
Co‐operation during induction ‐ Low sensory stimulation vs. control (Passive) ICC = 0 · children
It is very uncertain whether the intervention changes co‐operation during induction ‐ Low sensory stimulation vs. control… (very low certainty).
1 finding from 1 review
Intervention not reported
Co‐operation during induction ‐ Mask introduction/exposure (Mask) ICC (number of children compliant) · children
It is very uncertain whether the intervention changes co‐operation during induction ‐ Mask introduction/exposure (Mask)… (very low certainty).
1 finding from 1 review
Intervention not reported
Anxiety during induction ‐ Video game vs. midazolam (Interactive) mYPAS. Scale from: 1 to 100. · children
1 finding from 1 review
Intervention not reported
Co‐operation during induction ‐ clowns/clown doctors vs. parental presence (Interactive) SAM ‐ arousal. Scale from: 1 to 5. · children
1 finding from 1 review
Intervention not reported
Anxiety during induction ‐ hypnosis vs. midazolam (Interactive) mYPAS < 24 · children
It is very uncertain whether the intervention changes anxiety during induction ‐ hypnosis vs. midazolam (Interactive)… (very low certainty).
1 finding from 1 review
Intervention not reported
Anxiety during induction ‐ Acupuncture for parents mYPAS. Scale from: 1 to 100. · parents with children
1 finding from 1 review
Intervention not reported
Co‐operation during induction ‐ Acupuncture for parents Perfect induction ICC=0 · parents with children
The intervention may leads to higher co‐operation during induction ‐ Acupuncture for parents Perfect… (low certainty).
1 finding from 1 review
Intervention not reported
Anxiety during induction ‐ Parental presence vs. no parental presence · children
1 finding from 1 review
Sudden cardiac death · participants with high risk of sudden cardiac death (primary prevention)
Amiodarone may leads to lower sudden cardiac death compared with placebo or no treatment (low certainty).
1 finding from 1 review
All‐cause mortality · participants with high risk of sudden cardiac death (secondary prevention)
Amiodarone showed no clear difference in all‐cause mortality compared with other antiarrhythmics (low certainty).
1 finding from 1 review
Sudden cardiac death · participants with high risk of sudden cardiac death (secondary prevention)
It is very uncertain whether amiodarone changes sudden cardiac death compared with beta blockers (very low certainty).
1 finding from 1 review